News tagged with abnormal genes
Researchers identify potential molecular target to prevent growth of cancer cells
Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor. This finding by researchers at the University of ...
Sep 16, 2011 |
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Scientists uncover role for cell scaffold in tumor formation
A group of scientists at the Instituto Gulbenkian de Ciencia, in Portugal, have uncovered a surprising link between the cell's skeleton and organ size. The team, led by Florence Janody, show in the journal ...
Jun 06, 2011 |
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Researchers looking at a rare disease make breakthrough that could benefit everyone
By working with Canadians of French ancestry who suffer a rare genetic disease, researchers have discovered how three genes contribute to abnormal growth, making a breakthrough that will improve our understanding of many ...
Mar 01, 2011 |
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Researchers create first molecule blocks key component of cancer genes' on-off switch
In the quest to arrest the growth and spread of tumors, there have been many attempts to get cancer genes to ignore their internal instruction manual. In a new study, a team led by Dana-Farber Cancer Institute scientists ...
Sep 24, 2010 |
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Hereditary kidney disease linked to genetic location
An in-depth study of a family with multiple generations affected by kidney disease has identified a previously unknown location for a gene abnormality causing focal segmental glomerulosclerosis (FSGS), according to a study ...
Jul 08, 2010 |
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A better genetic test for autism
A large study from Children's Hospital Boston and the Boston-based Autism Consortium finds that a genetic test that samples the entire genome, known as chromosomal microarray analysis, has about three times the detection ...
Mar 15, 2010 |
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Gene identified as cause of some forms of intellectual disability
A gene involved in some forms of intellectual disability has been identified by scientists at the Centre for Addiction and Mental Health (CAMH), as published this month in The American Journal of Human Genetics. The gene i ...
Dec 15, 2009 |
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Clinical tests begin on medication to correct Fragile X defect
NIH-supported scientists at Seaside Therapeutics in Cambridge, Mass., are beginning a clinical trial of a potential medication designed to correct a central neurochemical defect underlying Fragile X syndrome, the most common ...
Medicine & Health / Neuroscience
Nov 02, 2009 |
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Why antidepressants don't work for so many
More than half the people who take antidepressants for depression never get relief. Why? Because the cause of depression has been oversimplified and drugs designed to treat it aim at the wrong target, according to new research ...
Medicine & Health / Psychology & Psychiatry
Oct 23, 2009 |
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New chromosomal abnormality identified in leukemia associated with Down syndrome
Researchers identified a new chromosomal abnormality in acute lymphoblastic leukemia (ALL) that appears to work in concert with another mutation to give rise to cancer. This latest anomaly is particularly common in children ...
Oct 18, 2009 |
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Lung cancer oncogene holds key to turning off cancer stem cells
Scientists at the Mayo Clinic campus in Florida have found that the lung cancer oncogene PKCiota is necessary for the proliferation of lung cancer stem cells. These stem cells are rare and powerful master cells that manufacture ...
Sep 08, 2009 |
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A yeast cancer model for mapping cancer genes
Researchers have devised a scheme for identifying genes in yeast that could lead to the identification of new cancer genes in humans. The study is published online this week in the open-access journal PLoS Bi ...
Jul 28, 2009 |
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First potential pathogenic mutation for restless legs syndrome found
An international team of researchers led by scientists at the Mayo Clinic campus in Florida have found what they believe is the first mutated gene linked to restless legs syndrome, a common neurologic disorder.
Medicine & Health / Neuroscience
Jul 21, 2009 |
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Findings in epilepsy gene in animals may guide treatment directions for infants
Researchers studying a difficult-to-treat form of childhood epilepsy called infantile spasms have developed a line of mice that experiences seizures with features closely resembling those occurring in patients with infantile ...
Jun 01, 2009 |
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New therapeutic strategy could target toxic protein in most patients with Huntington's disease
Howard Hughes Medical Institute researchers have designed tiny RNA molecules that shut off the gene that causes Huntington's disease without damaging that gene's healthy counterpart, which maintains the health and vitality ...
Apr 09, 2009 |
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