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Cell & Microbiology Mar 15, 2024

Hormonally up-regulated neu-associated kinase (HUNK) unveils a new function in cellular transport regulation

Endocytosis is a crucial cellular process that facilitates cells to take up cargos by enclosing them in membrane-bound vesicles, which are transported to different parts of the cell via the endosomal system and deliver cargos ...

Bio & Medicine Mar 14, 2024

Using adavosertib-encapsulated MOFs for p53-mutated gallbladder cancer treatment via synthetic lethality

Since the revelation of poly(ADP-ribose) polymerase (PARP) inhibitors and their remarkable results in the treatment of BRCA1/2 mutant cancers, synthetic lethality (SL) in antitumor therapy has attracted increasing attention. ...

Bio & Medicine Mar 14, 2024

Engineered MgO nanoparticles: A promising path to synergistic cartilage and bone therapy

In a recent study published in Science Advances, researchers from Nanjing Drum Tower Hospital and others have unveiled a promising approach for treating osteoarthritis (OA) using engineered magnesium oxide (MgO) nanoparticles.

Bio & Medicine Mar 14, 2024

Nanozyme-enabled nanodecoys: A new strategy for fighting urinary tract infections

Urinary tract infections (UTIs), affecting millions worldwide, are predominantly caused by uropathogenic Escherichia coli (UPEC). These infections are characterized by bacterial adhesion and colonization in the urinary tract, ...

Bio & Medicine Mar 14, 2024

Scientists develop new multicellular scaffold strategy for treating tendon-bone injuries

According to a study published in Science Advances, a research group led by Prof. Wu Chengtie from the Shanghai Institute of Ceramics of the Chinese Academy of Sciences has developed a multicellular scaffold based on inorganic ...

Bio & Medicine Mar 14, 2024

New LCD nanoparticle therapy offers hope for burn victims

Severe burns can cause critical issues, including deep tissue damage and an increased risk of fatal conditions such as sepsis and organ failure. A major concern is the disruption of the intestinal barrier, leading to inflammation ...

Astrobiology Mar 13, 2024

Unraveling the origins of life: Scientists discover 'cool' sugar acid formation in space

A critical molecule for the metabolism of living organisms has been synthesized for the first time by University of Hawaiʻi at Mānoa researchers at low temperatures (10 K) on ice coated nanoparticles mimicking conditions ...

Analytical Chemistry Mar 13, 2024

New catalyst accelerates release of hydrogen from ammonia

Germany can probably only meet its demand for climate-friendly hydrogen by imports, for example, from South America or Australia. For such long-distance transport, hydrogen can be converted into ammonia.

Bio & Medicine Mar 13, 2024

Sugar-coated gold nanoparticles can quickly eliminate bacterial infections, no antibiotics required

If left to their own devices, bacteria on our teeth or wounded skin can encase themselves in a slimy scaffolding, turning into what is called biofilm. These bacteria wreak havoc on our tissue and, being shielded from antibiotic ...

Nanomaterials Mar 12, 2024

Researchers reveal ways to fine-tune nanoparticles and outline future areas of study

The demand for renewable energy sources is constantly growing fueling the development of catalytic-based technologies. By separating and forming chemical bonds, these technologies can be used to produce environmentally friendly ...

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