Search results for tyrosine phosphorylation

Cell & Microbiology Jul 10, 2023

Fluorescent tags allow live monitoring of growth factor signaling proteins inside living cells

Synthetic biologists from Rice University and Princeton University have demonstrated "live reporter" technology that can reveal the workings of networks of signaling proteins in living cells with far greater precision than ...

Biochemistry Nov 28, 2022

The first potent COQ8 inhibitor targets ubiquinone biosynthesis

A new collaborative study from the University of Eastern Finland, Washington University in St. Louis, University of Wisconsin–Madison, University of North Carolina at Chapel Hill and the Promega Corporation discloses the ...

Biochemistry Dec 20, 2021

Research reveals features that influence phase separation

Scientists at St. Jude Children's Research Hospital and Washington University in St. Louis are dissecting the fundamental principles of biological phase separation, a process that is a major mechanism governing how cells ...

Biochemistry Oct 27, 2020

Scientists reveal dual specificity of Vav2-SH2 protein

Recently, a research team led by Prof. Wang Junfeng from the High Magnetic Field Laboratory, Hefei Institutes of Physical Science revealed the dual specificity of Vav2-SH2 protein after investigating the specific recognition ...

Bio & Medicine Sep 17, 2020

Functional ion nanochannel-based approach to detect tyrosine phosphorylation

Tyrosine phosphorylation (pTyr) can initiate cellular signaling and govern cellular functions. Its dysregulation is implicated in many diseases, especially cancers. Specific detection of pTyr-is important for developing targeted ...

Bio & Medicine Apr 17, 2019

A light-activated remote control for cells

What if doctors had a remote control that they could use to steer a patient's own cells to a wound to speed up the healing process? Although such a device is still far from reality, researchers reporting in the ACS journal ...

Cell & Microbiology Jul 17, 2018

Anatomy of a protein kinase spine and how to break it

The post-translational addition of phosphate groups to serine, threonine and tyrosine residues is a fundamental strategy for regulating protein activities in eukaryotes. Eukaryotic protein kinases—the enzymes that catalyze ...

Cell & Microbiology Jul 10, 2018

Discovery of a new on/off switch affecting cell-to-cell communications

Cellular functions rely on several communications networks that allow cells to respond to signals affecting the organism. A new study published in Molecular Cell has revealed a mechanism that shuts down a major cell-to-cell ...

Biochemistry May 17, 2017

The structure of a pathogenic effector protein from Legionella pneumophila

London-based scientists have elucidated the structure of a large fragment of a bacterial protein, known as WipA, which is secreted by Legionella pneumophila. The work, recently published in the Journal of Biological Chemistry, ...

Biotechnology Apr 21, 2017

Discovery of parental factors that lead to asymmetric division of the zygote

An international group of plant biologists discovered for the first time on how factors arising from the mother and father in flowering plants cooperate to develop the shape of their child. Until now, it has been unknown ...

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