Search results for transcription initiation

Cell & Microbiology 2 hours ago

Memories of mitosis: Molecular mechanism that detects defects during cell division could aid cancer treatment

Every day, our cells are hard at work multiplying. Cell division is a precise process, but sometimes this process is impaired and diseases like cancer occur. Mitosis is one of the most important phases in the cell cycle. ...

Cell & Microbiology 7 hours ago

Bacterial RNAs have shorter lifetimes than expected

The decay of ribonucleic acid (RNA) is a crucial mechanism for controlling gene expression in response to environmental stresses. Researchers from the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität ...

Cell & Microbiology Mar 25, 2024

Gut microbiota and antibiotics: Missing puzzle piece discovered

The intricacies of how intestinal bacteria adapt to their environment have yet to be fully explored. Researchers from the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of California, ...

Molecular & Computational biology Mar 20, 2024

New insights on the transcriptional regulation of seed germination

Seeds remain in a dormant state, waiting for the right environmental conditions to germinate, thus increasing the probability of fragile seedling survival. The transition from a dry seed to a vegetative seedling is an irreversible ...

Cell & Microbiology Mar 20, 2024

New tuberculosis study offers a novel paradigm for understanding bacterial transcription

The bacterium behind tuberculosis is a wily foe, adept at bobbing and weaving around the immune system and antibiotics alike. Mycobacterium tuberculosis (Mtb) has been notoriously difficult to eradicate, often dormant in ...

Cell & Microbiology Mar 14, 2024

Researchers reveal dual-function mechanism of bacteriophage-derived protein AcrIIA15

In response to the efficient attacks of the host CRISPR-Cas system, bacteriophages have evolved various resistance strategies, including encoding anti-CRISPR (Acr) proteins. Since their initial discovery in 2013, over a hundred ...

Molecular & Computational biology Mar 13, 2024

Simple trick could improve accuracy of plant genetics research

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables—such as temperature—affect gene activity in plants.

Cell & Microbiology Mar 12, 2024

Exploring the transferability of extracytoplasmic function switches across bacterial species

Extracytoplasmic function sigma factors (ECFs) have been successfully used for constructing predictable artificial gene circuits in bacteria like Escherichia coli, but their transferability between species within the same ...

Molecular & Computational biology Mar 12, 2024

How a natural compound from sea squirts combats cancer

Numerous anti-cancer drugs function by targeting the DNA within cancerous cells, halting their proliferation. Yet, cancer cells occasionally develop mechanisms to repair the damage inflicted by these drugs, diminishing their ...

Evolution Mar 6, 2024

Synthetic DNA sheds light on mysterious difference between living cells at different points in evolution

"Random DNA" is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular ...

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