Search results for craniofacial development

Cell & Microbiology Apr 22, 2024

Pressure in the womb may influence facial development

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers.

Cell & Microbiology Apr 12, 2024

Scientists produce in vitro model of cell differentiation during early facial development

Mother Nature is an artist, but her craft of creating animal faces requires more than a paintbrush and palette. Such highly complex shapes originate from their respective transient neural crest cells.

Molecular & Computational biology Apr 11, 2024

Keys to the genome: Unlocking the package with 'pioneer transcription factors'

Scientists at the Montreal Clinical Research Institute have discovered the molecular mechanisms responsible for opening up the human genome and expressing new genes.

Bio & Medicine Mar 19, 2024

Research seeks to develop mRNA lipid nanoparticles for next-generation oral cancer tumor suppressor therapy

A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with ...

Plants & Animals Dec 12, 2023

Experts provide a new theory for why larger mammals tend to have longer faces

A horse walks into a bar and the bartender asks, "why the long face"? It's one of the oldest puns in the book, and there's no shortage of entertaining answers.

Bio & Medicine May 26, 2023

Nanorobotic system presents new options for targeting fungal infections

Infections caused by fungi, such as Candida albicans, pose a significant global health risk due to their resistance to existing treatments, so much so that the World Health Organization has highlighted this as a priority ...

Evolution Mar 17, 2023

Diversification of the ruminant skull—from microevolutionary processes to macroevolutionary patterns

Evolutionary biologists aim to form fundamental connections between microevolutionary processes and macroevolutionary patterns based on comparative datasets of population-level variation. In a new report on Science Advances, ...

Cell & Microbiology Feb 16, 2023

Better understanding of craniofacial birth defects opens new roads for regenerative medicine

Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. These craniofacial anomalies occur because of defects in neural crest cells, whose role is to give rise ...

Cell & Microbiology Jan 5, 2023

Weiss-Kruszka syndrome and the failure to establish neuronal identity

Weiss-Kruszka syndrome is a rare neurodevelopmental disorder characterized by craniofacial anomalies, developmental delay, and autistic features. Researchers at the Institute of Molecular Biotechnology (IMBA) of the Austrian ...

Cell & Microbiology Jul 11, 2022

New research uncovers key factor controlling ear development at early stages

A new King's-led study, published in the Proceedings of the National Academy of Sciences, has found that a single factor (a protein coding gene known as Sox8) can make non-ear cells adopt ear character during embryo development. ...

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