Many therapeutics for asthma and other obstructive lung diseases target the β2-adrenergic receptor (β2AR), a G protein-coupled receptor (GPCR) that rapidly supports airway relaxation when stimulated. Yet, overuse of these ...
In the heart there are two different subtypes of beta-adrenergic receptors—beta1 and beta2—which are activated by the stress hormones adrenaline and noradrenaline. They both trigger the strongest stimulation of the heart ...
Thyroid disease affects about 12 percent of the U.S. population. While many people with thyroid disease don't even know they have it, an overactive or underactive thyroid can cause a slew of problems, including weight gain ...
Two Americans won the Nobel Prize in chemistry Wednesday for studies of how the cells in our bodies pick up signals as diverse as hormones, smells, flavors and light—work that is key to developing better medicines.
Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with deep importance for biology and medicine. These papers, ...
Small details between "in vivo" and "in vitro" studies make for big differences in understanding diabetes and other secretory dysfunctions
