https://phys.org/ en-us Phys.org internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Researchers at Tel Aviv University have destroyed 90% of multiple myeloma blood cancer cells under laboratory conditions, and 60% in human tissues taken from patients at Rabin Medical Center (Belinson Hospital), using an RNA-based drug delivered to the cells by targeted lipid nanoparticles. https://phys.org/news/2023-07-drug-delivery-rna-therapy-cancer.html Bio & Medicine Mon, 31 Jul 2023 11:00:48 EDT news610020045 Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma. https://phys.org/news/2023-06-nanoparticles-small-interfering-rna-multiple.html Bio & Medicine Sat, 17 Jun 2023 03:30:01 EDT news606049788 Through X-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 (DYRK2) at the atomic level. This previously unreported biochemical interaction of curcumin leads to inhibition of DYRK2 that impairs cell proliferation and reduces cancer burden. https://phys.org/news/2018-07-crystal-reveals-curcumin-impairs-cancer.html Biochemistry Mon, 09 Jul 2018 16:32:28 EDT news450372740 Abingdon Health, a tenant at the University of Birmingham's bio-incubator, is developing a rapid diagnostic test for bovine mastitis, a common and serious health problem in dairy cows, which has an estimated £14-23 billion impact on the global dairy industry. https://phys.org/news/2018-05-rapid-diagnostic-bovine-mastitis-horizon.html Other Wed, 16 May 2018 08:33:12 EDT news445678384 An international team, including researchers from the UGR's anthropology group led by Prof. Miguel Cecilio Botella López of the Department of Legal Medicine, Toxicology and Physical Anthropology, has discovered the world's oldest known cases of breast cancer and multiple myeloma, a type of bone marrow cancer. The discoveries were made by conducting CT scans of two mummies found in the pharaonic necropolis of Qubbet el-Hawa in Aswan, Egypt. https://phys.org/news/2017-12-oldest-cases-breast-cancer-myeloma.html Archaeology Fri, 15 Dec 2017 07:07:13 EST news432544024 A compound found in green tea could have lifesaving potential for patients with multiple myeloma and amyloidosis, who face often-fatal medical complications associated with bone-marrow disorders, according to a team of engineers at Washington University in St. Louis and their German collaborators. https://phys.org/news/2017-02-green-tea-compound-halt-molecular.html Biochemistry Mon, 06 Feb 2017 12:17:26 EST news405605833 A research collaboration between Brigham and Women's Hospital (BWH) and Dana-Farber Cancer Institute (DFCI) has utilized nanomedicine technologies to develop a drug-delivery system that can precisely target and attack cancer cells in the bone, as well as increase bone strength and volume to prevent bone cancer progression. https://phys.org/news/2014-06-scientists-nanoparticles-bone-cancer-bones.html Bio & Medicine Mon, 30 Jun 2014 14:59:20 EDT news323359143 Early screening for prostate cancer could become as easy for men as personal pregnancy testing is for women, thanks to UC Irvine research published today in the Journal of the American Chemical Society. https://phys.org/news/2013-05-chemists-inexpensive-accurate-prostate-cancer.html Analytical Chemistry Wed, 22 May 2013 09:21:37 EDT news288433289 (Phys.org) —Proteins, unlike diamonds, aren't forever. And when they wear out, they need to be degraded in the cell back into amino acids, where they will be recycled into new proteins. Researchers at Rockefeller University and the Howard Hughes Medical Institute have identified a new way that the cell's protein recycler, the proteasome, takes care of unwanted and potentially toxic proteins, a finding that has implications for treating muscle wasting, neurodegeneration and cancer. https://phys.org/news/2013-04-scientists-protein-degradation.html Cell & Microbiology Fri, 26 Apr 2013 07:04:56 EDT news286178690 Researchers from the University of Notre Dame have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow. https://phys.org/news/2012-06-newly-engineered-nanoparticles-blood-cancer-treatment.html Bio & Medicine Fri, 15 Jun 2012 18:50:57 EDT news259005044 As the "recycling plant" of the cell, the proteasome regulates vitally important functions. When it is inhibited, the cell chokes on its own waste. Cancer cells, in particular, are very sensitive because they need the proteasome for their uncontrolled growth. Biochemists at the Technische Universitaet Muenchen (TUM) have now identified the lead structure of a new class of drugs that attacks the proteasome in an unusual way. New medication could be developed on the basis of this previously unknown binding mechanism. The scientists report their results in the scientific journal Angewandte Chemie. https://phys.org/news/2011-11-class-drugs-reversible-inhibition-proteasomes.html Biochemistry Tue, 22 Nov 2011 14:02:05 EST news241192893 Biologists at UC San Diego have identified the specific region in vertebrates where adult blood stem cells arise during embryonic development. https://phys.org/news/2010-02-biologists-image-birth-blood-forming-stem.html Cell & Microbiology Sun, 14 Feb 2010 13:00:06 EST news185372571