http://phys.org/ en-us Phys.org internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Decreasing blood levels of a protein that helps control inflammation may be a red flag that could help children avoid type 1 diabetes, researchers say. http://phys.org/news222947205.html Medicine & Health Mon, 25 Apr 2011 11:10:01 EST news222947205 We all have at one time or another experienced the typical signs of an infection: the fever, the listlessness, the lack of appetite. They are orchestrated by the brain in response to circulating cytokines, the signaling molecules of the immune system. But just how cytokines' reach extends beyond the almost impenetrable blood-brain barrier has been the topic of much dispute. http://phys.org/news182608736.html Medicine & Health Wed, 13 Jan 2010 12:39:32 EST news182608736 One feature of the "new influenza" is a sudden rise in temperature. Up to now it was not exactly understood how this reaction occurs. Scientists at the University of Bonn and the Technical University of Munich, Germany, have been able to shed light into the dark. They have identified a new signaling pathway via which certain viruses can trigger inflammatory reactions and fever. Their results have been published in the journal Nature Immunology. http://phys.org/news177597673.html Medicine & Health Mon, 16 Nov 2009 12:42:12 EST news177597673 Cytokines are small proteins secreted by cells that serve as molecular messengers between cells. Pro-inflammatory cytokines - which function in the immune system - may be involved in alcohol dependence (AD). A study of three polymorphisms of the interleukin-1 gene complex (IL-1) and one of the tumor necrosis factor-alpha (TNFα) has found that IL-1 may directly contribute to AD among Spanish Caucasian males. http://phys.org/news172513919.html Medicine & Health Fri, 18 Sep 2009 17:32:47 EST news172513919 Fibrosis is a key feature of chronic pancreatitis and pancreatic cancer. The extensive deposition of extracellular matrix proteins fosters the development of an exocrine and endocrine organ insufficiency, and accelerates progression of the tumour. Pancreatic stellate cells (PSC) are the principal effector cells in pancreatic fibrosis. They are activated by profibrogenic mediators, which include, for example, cytokines and ethanol metabolites. So far, there are no therapies available to interfere with fibrogenesis in the diseased organ. http://phys.org/news172397446.html Medicine & Health Thu, 17 Sep 2009 09:12:01 EST news172397446 An exploration of the molecular links between insulin resistance and inflammation may have revealed a novel target for diabetes treatment, say scientists at the John G. Rangos Sr. Research Center, Children's Hospital of Pittsburgh of UPMC. Their findings were published earlier this month in the online version of Diabetes, one of the journals of the American Diabetes Association. http://phys.org/news170504200.html Medicine & Health Wed, 26 Aug 2009 11:17:40 EST news170504200 (AP) -- The nation's richest prize in medicine and biomedical research was awarded Friday to three immune system researchers for work that led to new treatments for rheumatoid arthritis and diabetes. http://phys.org/news159796774.html Medicine & Health Fri, 24 Apr 2009 13:00:04 EST news159796774 Three specific biomarkers provide an accurate indication of the severity of Chikungunya fever (CHIKF), which is emerging as a threat in South-East Asia, the Pacific and Europe, according to research conducted in Singapore. http://phys.org/news155397190.html Biology Wed, 04 Mar 2009 13:53:42 EST news155397190 It's called the obesity paradox. Although obese people are more apt to suffer from inflammatory diseases, such as diabetes, heart disease, and stroke, they are also more likely to survive a major attack caused by one of those conditions. http://phys.org/news154882304.html Medicine & Health Thu, 26 Feb 2009 14:52:58 EST news154882304