http://phys.org/ en-us Phys.org internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. A recent study by Mount Sinai faculty suggests that a gene associated with onset of type-2 diabetes also decreases in Alzheimer's disease dementia cases. The research, led by Dr. Giulio Maria Pasinetti, MD, Ph.D., The Aidekman Family Professor in Neurology, and Professor of Psychiatry and Geriatrics and Adult Development at Mount Sinai School of Medicine, was published this week in the scientific journal, Archives of Neurology. http://phys.org/news158584038.html Medicine & Health Fri, 10 Apr 2009 12:08:36 EST news158584038 It's basically a given that diets loaded with fat can lead to considerable health problems. But a new study in the April issue of Cell Metabolism, a Cell Press publication, shows that in some cases diets that are high in both fat and protein can be even worse. http://phys.org/news158328667.html Biology Tue, 07 Apr 2009 13:11:35 EST news158328667 April 7, 2009 - Researchers at the Joslin Diabetes Center have shown for the first time that insulin plays a key role in suppressing levels of glucagon, a hormone involved in carbohydrate metabolism and regulating blood glucose levels. http://phys.org/news158328265.html Medicine & Health Tue, 07 Apr 2009 13:04:49 EST news158328265 An inflammatory factor already linked to several diseases, including pulmonary disease, lung cancer, and arthritis, may also be responsible for the insulin resistance that comes with obesity, according to a new study published in the April issue of Cell Metabolism, a Cell Press publication. http://phys.org/news158327353.html Medicine & Health Tue, 07 Apr 2009 12:50:24 EST news158327353 The London Centre for Nanotechnology will develop a new device to enable people living with HIV to monitor their own health and the effectiveness of their treatments, thanks to a £2 million EPSRC (Engineering and Physical Sciences Research Council) grant announced today. http://phys.org/news158234040.html Nanotechnology Mon, 06 Apr 2009 10:54:37 EST news158234040 It has so far not been proven that long-acting insulin analogues (LAIAs) have an advantage over conventional human insulin in the treatment of patients with type 2 diabetes. Even though the results of a 5-year study are available for one of the two LAIAs assessed (insulin glargine), the potential long-term benefits and harms of this drug class have still not been sufficiently investigated. This is the conclusion of a report by the German Institute for Quality and Efficiency in Health Care (IQWiG), Cologne, which was published in March 2009 and for which an English-language summary is now available. http://phys.org/news157973855.html Medicine & Health Fri, 03 Apr 2009 10:38:23 EST news157973855 (AP) -- A scientific journal is retracting a research paper published more than eight years ago that reported a gene therapy treatment had led to remission of Type 1 diabetes in rats and mice. http://phys.org/news157830096.html Medicine & Health Wed, 01 Apr 2009 18:42:19 EST news157830096 (PhysOrg.com) -- A new method developed by Cornell biological engineers offers an efficient way to make proteins for use in medicine or industry without the use of live cells. The proteins made in this way include many that cannot be produced by current biotechnology. http://phys.org/news157827444.html Biology Wed, 01 Apr 2009 17:57:48 EST news157827444 Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a process that controls the amount of fat that cells store for use as a back-up energy source. Disruption of this process allows cellular fat to accumulate — a key factor in age-related metabolic diseases such as obesity and type 2 diabetes. The study is published today in the online version of Nature. http://phys.org/news157815546.html Medicine & Health Wed, 01 Apr 2009 14:39:39 EST news157815546 Human trials under way at the University of Miami and other hospitals in Europe, Asia and Latin America using immature adult stem cells are showing promise for people with type 2 diabetes. http://phys.org/news157534107.html Medicine & Health Sun, 29 Mar 2009 08:29:23 EST news157534107 Where different ethnic groups store fat in their bodies may account for differences in the likelihood they'll develop insulin resistance and non-alcoholic fatty liver disease, researchers at UT Southwestern Medical Center have found. http://phys.org/news157352386.html Medicine & Health Fri, 27 Mar 2009 06:00:48 EST news157352386 Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress pathway. http://phys.org/news157205418.html Medicine & Health Wed, 25 Mar 2009 13:11:00 EST news157205418 The journal Biochemical and Biophysical Research Communications (BBRC), published by Elsevier, will publish an important review this week online, by M. Daniel Lane and colleagues at Johns Hopkins, building on the suggested link between the consumption of fructose and increased food intake, which may contribute to a high incidence of obesity and Type 2 diabetes. http://phys.org/news157187750.html Medicine & Health Wed, 25 Mar 2009 08:16:12 EST news157187750 Less than an hour of daily exercise reduces depressive symptoms and improves self esteem in overweight children, Medical College of Georgia researchers say. http://phys.org/news156619125.html Medicine & Health Wed, 18 Mar 2009 18:19:13 EST news156619125 Scientists are closer to understanding which proteins help control blood sugar, or glucose, during and after exercise. This understanding could lead to new drug therapies or more effective exercise to prevent Type 2 diabetes and other health problems associated with having high blood sugar. http://phys.org/news156614523.html Medicine & Health Wed, 18 Mar 2009 17:04:51 EST news156614523 With obesity reaching epidemic levels, researchers at the Ohio State University Medical Center are studying a potentially long-term treatment that involves injecting a gene directly into one of the critical feeding and weight control centers of the brain. http://phys.org/news155843941.html Medicine & Health Mon, 09 Mar 2009 18:59:53 EST news155843941 A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods. The report in the March issue of Cell Metabolism, a Cell Press publication, also suggests a way to prevent those ill effects. http://phys.org/news155309349.html Biology Tue, 03 Mar 2009 13:29:34 EST news155309349 A report in the March issue of Cell Metabolism, a Cell Press publication, has found that a signal known to play a role during fasting also switches on early in the fat tissue of obese mice as they progress toward type 2 diabetes. Moreover, treatments that block that "fasting signal" in fat prevent the animals' resistance to insulin, according to the researchers. http://phys.org/news155309238.html Biology Tue, 03 Mar 2009 13:28:17 EST news155309238 A major international diabetes study of more than 52,000 patients from eight countries has shown that using biphasic BIAsp 30 insulin resulted in significant clinical improvements and greater patient satisfaction. http://phys.org/news155232398.html Medicine & Health Mon, 02 Mar 2009 16:08:18 EST news155232398 The endocrinologic basis of pediatric critical illness hypergylcemia (CIH) differs depending on the disease processes. Researchers writing in BioMed Central's open access journal Critical Care describe how both peripheral insulin resistance and primary beta-cell dysfunction can cause CIH in children. http://phys.org/news154869651.html Medicine & Health Thu, 26 Feb 2009 11:21:47 EST news154869651 Research by kinesiology investigator Dustin Hittel, PhD, has proven that muscle in extremely obese individuals produces large amounts of a protein called myostatin, which normally inhibits muscle growth--suggesting that for Type 2 diabetics, and the very obese, the task of getting healthy may be more difficult than initially thought. http://phys.org/news154867730.html Medicine & Health Thu, 26 Feb 2009 10:49:23 EST news154867730 Researchers at the Genomics Institute of the Novartis Research Foundation (GNF) have identified a set of compounds that can trigger the proliferation of insulin-producing cells in the pancreas, using sophisticated high-throughput screening techniques. http://phys.org/news154789336.html Medicine & Health Wed, 25 Feb 2009 13:02:53 EST news154789336 Scientists have determined that a specific gene plays a role in the weight-gain response to a high-fat diet. The finding in an animal study suggests that blocking this gene could one day be a therapeutic strategy to reduce diet-related obesity and associated disorders, such as diabetes and liver damage, in humans. http://phys.org/news154712272.html Medicine & Health Tue, 24 Feb 2009 15:38:17 EST news154712272 Researchers at the University of Vermont Cardiovascular Research Institute, Colchester, Vermont have found that increased expression in the heart of plasminogen activator inhibitor type-1 (PAI-1) is profibrotic. The results, which appear in the March 2009 issue of Experimental Biology and Medicine, implicate PAI-1 overexpression, known to accompany insulin resistance and type 2 diabetes, as a factor contributing to the high incidence of heart failure after myocardial infarction in people with diabetes. http://phys.org/news154682145.html Medicine & Health Tue, 24 Feb 2009 07:16:15 EST news154682145 (PhysOrg.com) -- Scientists funded by the Biotechnology and Biological Sciences Research Council have harnessed a new drug discovery tool to identify a new player in the body's insulin secretion process. This finding could spark a completely new class of drugs to treat type 2 diabetes. http://phys.org/news154538750.html Biology Sun, 22 Feb 2009 15:27:13 EST news154538750 Scientists at the Gladstone Institutes of Cardiovascular Disease (GICD) have found that an enzyme associated with the synthesis of fat in the body is also an element in healthy skin and hair. http://phys.org/news153736642.html Chemistry Fri, 13 Feb 2009 08:38:04 EST news153736642 According to a recent study published online in The FASEB Journal, diets rich in omega-3 fatty acids protect the liver from damage caused by obesity and the insulin resistance it provokes. This research should give doctors and nutritionists valuable information when recommending and formulating weight-loss diets and help explain why some obese patients are more likely to suffer some complications associated with obesity. Omega-3 fatty acids can be found in canola oil and fish. http://phys.org/news153672709.html Medicine & Health Thu, 12 Feb 2009 14:54:21 EST news153672709 AUGUSTA, Ga. - Knocking out one gene that contributes to insulin resistance appears to prevent much of the cardiovascular damage typically associated with obesity, researchers say. http://phys.org/news153578790.html Medicine & Health Wed, 11 Feb 2009 12:49:21 EST news153578790 Researchers have found what appears to be a major culprit behind the loss of insulin-producing β cells from the pancreases of people with diabetes, a critical event in the progression of the disease. http://phys.org/news152893015.html Biology Tue, 03 Feb 2009 14:17:58 EST news152893015 A Northwestern University-led research team reports that insulin, by shielding memory-forming synapses from harm, may slow or prevent the damage and memory loss caused by toxic proteins in Alzheimer's disease. http://phys.org/news152818063.html Medicine & Health Mon, 02 Feb 2009 17:28:15 EST news152818063