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A study of thousands of people with bipolar disorder suggests that genetic risk factors may influence the decision to attempt suicide. http://phys.org/news220534540.html Medicine & Health Mon, 28 Mar 2011 12:35:58 EST news220534540 Physical ill-health is rife among the severely mentally ill in Britain, according to new research published today by the University of East Anglia (UEA). http://phys.org/news219898532.html Medicine & Health Mon, 21 Mar 2011 03:55:45 EST news219898532 Despite international variation in prevalence rates of bipolar spectrum disorder, the severity and associated disorders are similar and treatment needs are often unmet, especially in low-income countries, according to a report in the March issue of Archives of General Psychiatry. http://phys.org/news218739040.html Medicine & Health Mon, 07 Mar 2011 16:50:52 EST news218739040 A new study provides fascinating insight into the genetic basis of bipolar disorder, a highly heritable mood disorder characterized by recurrent episodes of mania and depression. The research, published by Cell Press online February 24 in the American Journal of Human Genetics, identifies a previously unrecognized susceptibility factor for bipolar disorder. http://phys.org/news218372792.html Medicine & Health Thu, 03 Mar 2011 11:20:02 EST news218372792 Lithium, introduced in the late 1940's, was the first "wonder drug" in psychiatry. It was the first medication treatment for the manic and depressive episodes of bipolar disorder and it remains among one of the most effective treatments for this disorder. http://phys.org/news217081783.html Medicine & Health Wed, 16 Feb 2011 12:30:01 EST news217081783 A study of nearly 300 women with bipolar disorder showed that those reporting flare-ups of mood symptoms before menstruation had more depressive episodes and more severe symptoms during the following year, compared with bipolar women without premenstrual mood changes. http://phys.org/news217061207.html Medicine & Health Wed, 16 Feb 2011 07:00:02 EST news217061207 People with psychotic disorders, such as schizophrenia or bipolar disorder, are 12 times more likely to commit suicide than average, according to research released today by King's Health Partners. http://phys.org/news210875868.html Medicine & Health Mon, 06 Dec 2010 17:20:12 EST news210875868 Among patients with depression, the presence of many aspects of illness which may be associated with bipolar disorder does not appear to be associated with treatment resistance—evidence against the common hypothesis that some cases of difficult-to-treat depression are actually unrecognized bipolar disorder, according to a report posted online today that will appear in the April 2011 print issue of Archives of General Psychiatry. However, many patients with depression also report psychotic-like symptoms, such as hearing voices or believing they are being spied on or plotted against, and those who do are less likely to respond to treatment. http://phys.org/news210875590.html Medicine & Health Mon, 06 Dec 2010 17:20:01 EST news210875590 Veterans diagnosed with any psychiatric illness appear to have an elevated risk of suicide, and men with bipolar disorder and women with substance abuse disorders may have a particularly high risk, according to a report in the November issue of Archives of General Psychiatry. http://phys.org/news207851459.html Medicine & Health Mon, 01 Nov 2010 17:31:15 EST news207851459 Researchers at the University of Illinois at Chicago are the first to use brain imaging to examine the effects of emotion on working memory function in children with pediatric bipolar disorder or attention deficit hyperactivity disorder. http://phys.org/news206115228.html Medicine & Health Tue, 12 Oct 2010 15:14:03 EST news206115228 A new study from Sweden's Karolinska Institutet suggests that bipolar disorder - or manic-depressive disorder - does not increase the risk of committing violent crime. Instead, the over-representation of individuals with bipolar disorder in violent crime statistics is almost entirely attributable to concurrent substance abuse. http://phys.org/news203076591.html Medicine & Health Tue, 07 Sep 2010 11:10:03 EST news203076591 Interviews with members of more than 5,000 representative U.S. households as part of the National Comorbidity Survey Replication found that nearly 40 percent of those with major depressive disorder may actually have subthreshold hypomania, defined as a discrete period of increased energy, activity, and euphoria or irritability that is not related to impairment in daily activities. http://phys.org/news201194111.html Medicine & Health Mon, 16 Aug 2010 16:15:29 EST news201194111 A single intravenous dose of the anesthetic agent ketamine appears to reduce symptoms of depression within 40 minutes among those with bipolar disorder who have not responded to other treatments, according to a report in the August issue of Archives of General Psychiatry. http://phys.org/news199986110.html Medicine & Health Mon, 02 Aug 2010 17:30:01 EST news199986110 (PhysOrg.com) -- When it comes to bipolar disorder, a successful diagnosis can be challenging. http://phys.org/news197204536.html Medicine & Health Thu, 01 Jul 2010 12:40:02 EST news197204536 Lithium has been established for more than 50 years as one of the most effective treatments for manic depression, clinically termed bipolar disorder. http://phys.org/news195985688.html Medicine & Health Thu, 17 Jun 2010 09:28:30 EST news195985688 Nearly half of patients hospitalized with bipolar disorder may suffer from hypertension, and the younger a person is diagnosed with the psychiatric condition the more likely they are to develop high blood pressure, according to a recent Michigan State University study. http://phys.org/news195406571.html Medicine & Health Thu, 10 Jun 2010 16:36:31 EST news195406571 Lithium is the most effective treatment for bipolar disorder. http://phys.org/news195196053.html Medicine & Health Tue, 08 Jun 2010 06:07:58 EST news195196053 Though it has been prescribed for over 50 years to treat bipolar disorder, there are still many questions regarding exactly how lithium works. However, in a study appearing in this month's Journal of Lipid Research, researchers have provided solid evidence that lithium reduces brain inflammation by adjusting the metabolism of the health-protective omega-3-fatty acid called DHA. http://phys.org/news193663862.html Medicine & Health Fri, 21 May 2010 12:31:21 EST news193663862 (Garrison, NY) Shifting children from the controversial diagnosis of bipolar disorder to one that more accurately reflects their symptoms will not by itself decrease the rate of psychopharmacologic treatment and is not enough to help troubled children flourish, according to a commentary in the New England Journal of Medicine by researchers at The Hastings Center, a bioethics research institute, and a physician-researcher at Stony Brook University School of Medicine. http://phys.org/news193493276.html Medicine & Health Wed, 19 May 2010 17:00:01 EST news193493276 A study from Rhode Island Hospital finds patients who were "over-diagnosed" with bipolar disorder were more likely to have received disability payments and for a longer period of time. The researchers propose a link between these unconfirmed cases of bipolar disorder and the receipt of the payments. Their study and findings are published in the June 2010 edition of the Journal of Nervous and Mental Disease. http://phys.org/news193493896.html Medicine & Health Wed, 19 May 2010 13:50:01 EST news193493896 (PhysOrg.com) -- Genetic testing may rise to a new level with the findings of Indiana University School of Medicine researchers whose "prototype" for laboratory testing for bipolar disorder appears today in the online edition of the American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. http://phys.org/news190295677.html Medicine & Health Mon, 12 Apr 2010 13:50:36 EST news190295677 A study of the genetics of common diseases including diabetes, heart disease and bipolar disorder has found that commonly occurring copy number variations - duplicated or missing chunks of DNA in our genome - are unlikely to play a major role in such diseases. The research, funded by the Wellcome Trust, is published online today in the journal Nature. http://phys.org/news189258097.html Medicine & Health Wed, 31 Mar 2010 13:00:28 EST news189258097 A study from Rhode Island Hospital has shown that a widely-used screening tool for bipolar disorder may incorrectly indicate borderline personality disorder rather than bipolar disorder. In the article that appears online ahead of print in the Journal of Clinical Psychiatry, the researchers question the effectiveness of the Mood Disorder Questionnaire (MDQ). http://phys.org/news188740652.html Medicine & Health Thu, 25 Mar 2010 13:30:18 EST news188740652 (Garrison, NY) Troubled children diagnosed with bipolar disorder may fare better with a different diagnosis, according to researchers at The Hastings Center. http://phys.org/news188147995.html Medicine & Health Thu, 18 Mar 2010 16:30:01 EST news188147995 A one-page, 27-item questionnaire that is available free online is a valid and effective tool to help primary care doctors screen patients for four common psychiatric illnesses, a study led by University of North Carolina at Chapel Hill researchers concludes. http://phys.org/news187292690.html Medicine & Health Mon, 08 Mar 2010 18:10:01 EST news187292690 Offspring of two parents with schizophrenia or bipolar disorder appear more likely to develop the same illness or another psychiatric condition than those with only one parent with psychiatric illness, according to a report in the March issue of Archives of General Psychiatry. http://phys.org/news186684960.html Medicine & Health Mon, 01 Mar 2010 17:30:13 EST news186684960 (PhysOrg.com) -- Bipolar disorder, also known as manic depression, refers to severe episodes of mood disturbance ranging from depression to elation that affect a person's ability to function normally. http://phys.org/news185626091.html Medicine & Health Wed, 17 Feb 2010 11:00:01 EST news185626091 Scientists have identified a gene they say is a strong candidate for involvement in premenstrual dysphoric disorder (PMDD) and other maladies associated with the natural flux in hormones during the menstrual cycle. In a paper published Monday in the Proceedings of the National Academy of Sciences, Rockefeller University researchers detail experiments in mice showing that a common human variant of the gene increases anxiety, dampens curiosity and tweaks the effects of estrogen on the brain, impairing memory. If applied in the clinic, the work could help diagnose and treat cognitive and mood disorders related to the menstrual cycle and inform treatments during menopause, such as hormone replacement therapy, researchers say. http://phys.org/news184944040.html Medicine & Health Tue, 09 Feb 2010 13:20:59 EST news184944040 (PhysOrg.com) -- The Greek philosopher Aristotle once said "there is no great genius without a mixture of madness," and now there is some scientific evidence that there is a link between mania and high IQ and creativity, since a study of over 700,000 subjects showed those who scored the highest grades were almost four times more likely to develop bipolar disorder in their adult lives than those scoring average grades. http://phys.org/news184573059.html Medicine & Health Fri, 05 Feb 2010 08:40:01 EST news184573059 Schizophrenia and bipolar disorder affect tens of millions of individuals around the world. These disorders have a typical onset in the early twenties and in most cases have a chronic or recurring course. Neither disorder has an objective biological marker than can be used to make diagnoses or to guide treatment. http://phys.org/news184498051.html Medicine & Health Thu, 04 Feb 2010 09:27:46 EST news184498051