http://phys.org/ en-us Phys.org provides the latest news from Karolinska Institutet Tiny particles filled with a drug could be a new tool for treating cancer in the future. A new study published by Swedish scientists in Particle & Particle Systems Characterization shows how such nanoparticles can be combined to secure the effective delivery of cancer drugs to tumour cells – and how they can be given properties to make them visible in MR scanners and thus rendered trackable. http://phys.org/news281275577.html Nanotechnology Thu, 28 Feb 2013 12:06:33 EST news281275577 Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA. http://phys.org/news280917307.html Biology Sun, 24 Feb 2013 13:00:24 EST news280917307 Scientists at Karolinska Institutet in Sweden have made a large step towards the understanding of how human genes are regulated. In a new study, published in the journal Cell, they identified the DNA sequences that bind to over four hundred proteins that control expression of genes. This knowledge is required for understanding of how differences in genomes of individuals affect their risk to develop disease. http://phys.org/news277643362.html Biology Thu, 17 Jan 2013 12:00:01 EST news277643362 Scientists at Karolinska Institutet in Sweden have identified two molecules that play an important role in the survival and production of nerve cells in the brain, including nerve cells that produce dopamine. The discovery, which is published in the journal Nature Chemical Biology, may be significant in the long term for the treatment of several diseases, such as Parkinson's disease. http://phys.org/news275488513.html Chemistry Sun, 23 Dec 2012 13:00:28 EST news275488513 Scientists at Karolinska Institutet in Sweden describe in a new study how so-called DNA origami can enhance the effect of certain cytostatics used in the treatment of cancer. With the aid of modern nanotechnology, scientists can target drugs direct to the tumour while leaving surrounding healthy tissue untouched. http://phys.org/news266760119.html Nanotechnology Thu, 13 Sep 2012 13:02:22 EST news266760119 (Phys.org) -- Using data supplied by a mobile operator, researchers at Karolinska Institutet have shown that population movements after the 2010 Haiti earthquake followed regular patterns. This information can be used to predict beforehand the movements of people after a disaster, and thus improves chances for aid to be delivered to the right places at the right time. http://phys.org/news259307138.html Technology Tue, 19 Jun 2012 06:45:47 EST news259307138 (PhysOrg.com) -- A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism behind putative side effects of the so-called PARP inhibitors, and can play an important role in the development of novel tailor-made cancer drugs. The study is presented in the journal Nature Biotechnology, and will hopefully contribute to new cancer therapies with fewer detrimental side effects. http://phys.org/news248962366.html Biology Mon, 20 Feb 2012 12:13:05 EST news248962366 (PhysOrg.com) -- Researchers at the Swedish medical university Karolinska Institutet have developed a new method for counting molecules. Quantifying the amounts of different kinds of RNA and DNA molecules is a fundamental task in molecular biology as these molecules store and transfer the genetic information in cells. Thus, improved measurement techniques are crucial for understanding both normal and cancer cells. http://phys.org/news241081293.html Biology Mon, 21 Nov 2011 07:02:22 EST news241081293 Difficulties in assessing the patients work capacity, non-medical problems, and handling situations in which the patients have different opinions about the need for sick leave are some of the challenges that physicians meet in their daily work, according to a new doctoral thesis from Karolinska Institutet. http://phys.org/news223022074.html Medicine & Health Tue, 26 Apr 2011 07:34:59 EST news223022074 Pedestrian disability and fatality as a consequence of car crashes is a large global health problem. A new doctoral thesis from Karolinska Institutet now shows that upper-body collision with the car's lower windscreen is a common cause of severe injuries and deaths in adults, especially in those accidents where the head is struck. Children injured by cars are mostly hit by the hood. http://phys.org/news221206476.html Medicine & Health Tue, 05 Apr 2011 07:14:52 EST news221206476 sometimes referred to as placebo - is just as beneficial as real acupuncture for treating nausea in cancer patients undergoing radiotherapy, according to a study from Karolinska Institutet and Linkoping University in Sweden. Patients, who received only standard care including medications for nausea, felt significant more nausea than patients in both the acupuncture groups. http://phys.org/news220184580.html Medicine & Health Thu, 24 Mar 2011 11:23:16 EST news220184580 Research from Karolinska Institutet in Sweden shows, that a specific inflammatory factor may be important in the development of the heart valve disease aortic stenosis. The results suggest that anti-inflammatory medication could be a possible new treatment. http://phys.org/news219395736.html Medicine & Health Tue, 15 Mar 2011 08:15:50 EST news219395736 Neurodegenerative diseases like Alzheimer's and Parkinson's are partly attributable to brain inflammation. Researchers at Karolinska Institutet now demonstrate in a paper published in Nature that a well-known family of enzymes can prevent the inflammation and thus constitute a potential target for drugs. http://phys.org/news218959477.html Medicine & Health Thu, 10 Mar 2011 06:40:01 EST news218959477 A study from Karolinska Institutet has shown that the body's ability to break down medicines may be closely related to exposure to sunlight, and thus may vary with the seasons. The findings offer a completely new model to explain individual differences in the effects of drugs, and how the surroundings can influence the body's ability to deal with toxins. http://phys.org/news218870084.html Medicine & Health Wed, 09 Mar 2011 05:40:01 EST news218870084 Parents who are both present and engaged are the very best way of preventing teenagers from consuming large quantities of alcohol. Adolescents who smoke, stay out with their friends and have access to alcohol - from their parents, for example - when they are as young as 13 are at greater risk of becoming binge drinkers in their late teens, reveals a new thesis from Karolinska Institutet. http://phys.org/news218705987.html Medicine & Health Mon, 07 Mar 2011 07:50:02 EST news218705987