https://phys.org/ en-us Phys.org internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Researchers at Tel Aviv University have destroyed 90% of multiple myeloma blood cancer cells under laboratory conditions, and 60% in human tissues taken from patients at Rabin Medical Center (Belinson Hospital), using an RNA-based drug delivered to the cells by targeted lipid nanoparticles. https://phys.org/news/2023-07-drug-delivery-rna-therapy-cancer.html Bio & Medicine Mon, 31 Jul 2023 11:00:48 EDT news610020045 Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma. https://phys.org/news/2023-06-nanoparticles-small-interfering-rna-multiple.html Bio & Medicine Sat, 17 Jun 2023 03:30:01 EDT news606049788 Through X-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 (DYRK2) at the atomic level. This previously unreported biochemical interaction of curcumin leads to inhibition of DYRK2 that impairs cell proliferation and reduces cancer burden. https://phys.org/news/2018-07-crystal-reveals-curcumin-impairs-cancer.html Biochemistry Mon, 09 Jul 2018 16:32:28 EDT news450372740 A compound found in green tea could have lifesaving potential for patients with multiple myeloma and amyloidosis, who face often-fatal medical complications associated with bone-marrow disorders, according to a team of engineers at Washington University in St. Louis and their German collaborators. https://phys.org/news/2017-02-green-tea-compound-halt-molecular.html Biochemistry Mon, 06 Feb 2017 12:17:26 EST news405605833 A research collaboration between Brigham and Women's Hospital (BWH) and Dana-Farber Cancer Institute (DFCI) has utilized nanomedicine technologies to develop a drug-delivery system that can precisely target and attack cancer cells in the bone, as well as increase bone strength and volume to prevent bone cancer progression. https://phys.org/news/2014-06-scientists-nanoparticles-bone-cancer-bones.html Bio & Medicine Mon, 30 Jun 2014 14:59:20 EDT news323359143 (Phys.org) —Proteins, unlike diamonds, aren't forever. And when they wear out, they need to be degraded in the cell back into amino acids, where they will be recycled into new proteins. Researchers at Rockefeller University and the Howard Hughes Medical Institute have identified a new way that the cell's protein recycler, the proteasome, takes care of unwanted and potentially toxic proteins, a finding that has implications for treating muscle wasting, neurodegeneration and cancer. https://phys.org/news/2013-04-scientists-protein-degradation.html Cell & Microbiology Fri, 26 Apr 2013 07:04:56 EDT news286178690 Researchers from the University of Notre Dame have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow. https://phys.org/news/2012-06-newly-engineered-nanoparticles-blood-cancer-treatment.html Bio & Medicine Fri, 15 Jun 2012 18:50:57 EDT news259005044 Biologists at UC San Diego have identified the specific region in vertebrates where adult blood stem cells arise during embryonic development. https://phys.org/news/2010-02-biologists-image-birth-blood-forming-stem.html Cell & Microbiology Sun, 14 Feb 2010 13:00:06 EST news185372571