Doctors see more children with inflammatory bowel diseaseMarch 29th, 2011 in Medicine & Health / Diseases, Conditions, Syndromes
Once a medical rarity in children, inflammatory bowel disease today is increasingly common in kids, but many of them may not be diagnosed in a timely manner, according to experts from the Pediatric Inflammatory Bowel Disease Center at Johns Hopkins Children's.
Gastroenterologists there say that many of the hundreds of children they see were referred to them only after months of repeated visits to their primary-care physicians for symptoms mistakenly attributed to common GI ailments like viral gastritis.
Inflammatory bowel disease is still considered an adult condition and is rarely on pediatricians radars, says Maria Oliva-Hemker, M.D., chief of the Gastroenterology & Nutrition division at Hopkins Childrens and director of the comprehensive IBD center there. Fifty years ago, IBD was almost exclusively diagnosed in adults. These days, treating children with IBD is business as usual in our clinics.
The two main forms of IBD are Crohns disease (CD) and ulcerative colitis (UC). For unknown reasons, Crohns disease seems to be rising more rapidly in children than ulcerative colitis, Oliva-Hemker says. Children with CD also tend to be diagnosed later than those with ulcerative colitis because the most common symptom is vague abdominal pain rather than the more suggestive bloody stools seen in ulcerative colitis, she notes.
Delays in treatment can make IBD worse and lead to severe anemia from gastrointestinal bleeding, poor food absorption, malnutrition and stunted growth. In advanced cases, IBD can cause serious damage to the colon and small intestine that requires surgery.
To prevent dangerous delays in diagnosis and treatment, Oliva-Hemker says the following symptoms especially if they keep coming back or never fully go away should prompt a visit to a specialist:
nausea and/or vomiting
poor appetite and weight loss
poor growth, especially in younger children
pale skin, rapid heartbeat, fatigue and dizziness, all of which could indicate chronic anemia from GI bleeding
a family history of IBD up to 30 percent of childhood cases have genetic roots
Oliva-Hemker advises pediatricians who suspect IBD to obtain routine blood tests to check for anemia and inflammation markers like elevated sedimentation rate and C-reactive protein. The diagnosis can usually be confirmed with an endoscopy and colonoscopy.
IBD is most commonly diagnosed in school-age children and teens, but Hopkins Childrens gastroenterologists say that they have seen the disease in a growing number of children younger than 5 years of age.
More than 100,000 children in the United States have IBD, according to the Crohns & Colitis Foundation of America. A 2003 study published in The Journal of Pediatrics reported a surprisingly high rate of IBD among children in Wisconsin the highest in the world at that point 7.5 cases per 100 000, with a CD rate of 4.56 and a UC rate of 2.14.
Scientists believe that IBD is triggered by an overactive immune system that mistakenly attacks the colon and small intestine. The reasons driving the rise of childhood IBD remain unclear, but genetic and environmental factors are clearly at play, experts say. Because genetic makeup does not change drastically in populations over short periods of time, it is more likely that changing environmental factors are triggering new cases in genetically predisposed children, the researchers say.
Provided by Johns Hopkins University
"Doctors see more children with inflammatory bowel disease." March 29th, 2011. http://phys.org/news/2011-03-doctors-children-inflammatory-bowel-disease.html