The not-so-sweet truth about sugar -- a risk choice?

November 22nd, 2010 in Medicine & Health / Health
This is Richard J. Johnson, M.D., of the division of renal diseases and hypertension at the University of Colorado. Credit: American Society of Nephrology


This is Richard J. Johnson, M.D., of the division of renal diseases and hypertension at the University of Colorado. Credit: American Society of Nephrology

More and more people have become aware of the dangers of excessive fructose in diet. A new review on fructose in an upcoming issue of the Journal of the American Society of Nephrology (JASN) indicates just how dangerous this simple sugar may be.

Richard J. Johnson, MD and Takahiko Nakagawa, MD (Division of Renal Diseases and Hypertension, University of Colorado) provide a concise overview of recent clinical and experimental studies to understand how excessive amounts of , present in added sugars, may play a role in , diabetes, obesity, and chronic kidney disease (CKD).

Dietary fructose is present primarily in added dietary sugars, honey, and fruit. Americans most frequently ingest fructose from sucrose, a disaccharide containing 50% fructose and 50% glucose bonded together, and (HFCS), a mixture of free fructose and free glucose, usually in a 55/45 proportion. With the introduction of HFCS in the 1970s, an increased intake of fructose has occurred and obesity rates have risen simultaneously.

The link between excessive intake of fructose and is becoming increasingly established. However, in this review of the literature, the authors conclude that there is also increasing evidence that fructose may play a role in hypertension and renal disease. "Science shows us there is a potentially negative impact of excessive amounts of and high fructose corn syrup on cardiovascular and kidney health," explains Dr. Johnson. He continues that "excessive fructose intake could be viewed as an increasingly risky food and beverage additive."

Concerned that physicians may be overlooking this health problem when advising CKD patients to follow a low protein diet, Dr. Johnson and Dr. Nakagawa recommend that low protein diets include an attempt to restrict added sugars containing fructose.

More information: The article, entitled "The Effect of Fructose on Renal Biology and Disease," will appear online on November 29, 2010, doi:10.1681/ASN.2010050506

Provided by American Society of Nephrology

"The not-so-sweet truth about sugar -- a risk choice?." November 22nd, 2010. http://phys.org/news/2010-11-not-so-sweet-truth-sugar-choice.html