The Whitehead Institute for Biomedical Research became financially independent from MIT in 1982. The Whitehead Institute for Biomedical Research while fiscally independent is attached to MIT via the faculty members from MIT's Biology Department. It is a distinguished biomedical research institute and one of the leading genome research centers in the world. Scientists/Professors at Whitehead are distinguished in their field and have received numerous science awards and grants from the NIH as well as other private endowments. Whitehead publishes the Paradigm Magazine and displays current biomedical research on-line.

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How cells manage their mRNA stockpile and its output

In a typical cell, genes encoded in DNA are used to make messenger RNA (mRNA), which is used to make proteins, and this process of gene expression keeps the cell running. Gene expression is regulated in each cell such that ...

How signaling proteins get to the mitochondrial surface

Mitochondria are organelles that are known for providing the energy currency that fuels chemical reactions within cells, but they are also involved in other important processes vital for cell health including the innate immune ...

How cells accurately assemble complex machinery

Proteins are the workhorses of the cell, carrying out functions to keep everything running smoothly. Some proteins work on their own, but in other cases many proteins assemble together to create a complex machine. These proteins ...

CLAMP complex helps parasites enter human cells

Apicomplexan parasites are a group of single-celled organisms responsible for several serious and prevalent diseases, from malaria, to a severe childhood diarrhea (cryptosporidiosis), to toxoplasmosis—a disease that endangers ...

A not-so-selfish 'genetic parasite' helps to preserve fertility

Ribosomal DNA (rDNA) sequences are essential parts of many species' genomes. The highly repetitive nature of these DNA sequences makes them susceptible to shrinkage over time—and if they shrink too much, cells die. If rDNA ...

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