Understanding the circadian clocks of individual cells

Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means. These findings, published online May 1 in PNAS and May 27 in eLife, ...

Viewing dopamine receptors in their native habitat

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells. But despite their importance in physiology ...

Urge to merge: Understanding how cells fuse

Scientists have known for a decade that cells that fuse with others to perform their essential functions—such as muscle cells that join together to make fibers—form long projections that invade the territory of their ...

Researchers use snake venom to solve structure of muscle protein

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction. The report, published today in Neuron, may lead to improved understanding of muscle-weakening ...

First structure of human cotransporter protein family member solved

In work that could someday improve treatments for epilepsy, UT Southwestern scientists have published the first three-dimensional structure of a member of a large family of human proteins that carry charged particles—ions—across ...

Implanted memories teach birds a song

A father holds up his newborn, their faces only inches apart, and slowly repeats the syllables "da" and "dee." After months of hearing these sounds, the baby begins to babble and gradually "da da da" is refined to the word ...

Newly identified bacteria-killing protein needs vitamin A to work

People who have inadequate vitamin A in their diets are more susceptible to skin infection, yet how that vitamin affects skin immunity has been unclear. In a study published today, UT Southwestern researchers shed some light ...

Scientists find method to boost CRISPR efficiency

Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases.

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