Born with a retinal disease that made him legally blind, and would eventually leave him totally sightless, the nine-year-old boy used to sit in the back of the classroom, relying on the large print on an electronic ...
Oct 25, 2009
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Double-strand breaks in DNA happen every time a cell divides and replicates. Depending on the type of cell, that can be pretty often. Many proteins are involved in everyday DNA repair, but if they are mutated, ...
Feb 03, 2013
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It happens to everyone: You stay up late one night to finish an assignment, and the next day, you're exhausted. Humans aren't unique in that; all animals need sleep, and if they don't get it, they must make ...
Mar 07, 2013
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(PhysOrg.com) -- A growing body of evidence underscores the importance of human gut bacteria in modulating human health, metabolism, and disease. Yet bacteria are only part of the story. Viruses that infect ...
Mar 19, 2012
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In the first study of its kind, a team of researchers led by faculty at the Perelman School of Medicine at the University of Pennsylvania and the Baylor College of Medicine, has analyzed data on the impact ...
Jan 07, 2013
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Brown fat is a hot topic, pardon the pun. Brown fats cells, as opposed to white fat cells, make heat for the body, and are thought to have evolved to help mammals cope with the cold. But, their role in generating ...
Mar 14, 2013
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The recently published genome sequences of seven well-studied ant species are opening up new vistas for biology and medicine. A detailed look at molecular mechanisms that underlie the complex behavioral differences ...
Feb 13, 2013
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(PhysOrg.com) -- The molecular pathway that carries time-of-day signals from the body's internal clock to ultimately guide daily behavior is like a black box, says Amita Sehgal, PhD, the John Herr Musser Professor ...
Feb 07, 2012
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(Phys.org)—Epigenetics - the science of how gene activity can be altered without changes in the genetic code - plays a critical role in every aspect of life, from the differentiation of stem cells to the ...
Jan 08, 2013
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Amyloid fibers are protein aggregates associated with numerous neurodegenerative diseases, including Parkinson's disease, for which there are no effective treatments.
Jun 19, 2012
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(Phys.org)—Calpain, a calcium-regulated enzyme, is essential to a host of cellular processes, but can cause severe problems in its overactivated state. It has been implicated as a factor in muscular dystrophy, ...
Dec 27, 2012
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Fifty years ago, British researcher John Gurdon demonstrated that genetic material from non-reproductive, or somatic, cells could be reprogrammed into an embryonic state when transferred into an egg. In 2006, ...
Nov 15, 2012
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(Phys.org)—Several fatal brain disorders, including Parkinson's disease, are connected by the misfolding of specific proteins into disordered clumps and stable, insoluble fibrils called amyloid. Amyloid ...
Nov 19, 2012
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