University of Pennsylvania School of Medicine

Genetic variation in human gut viruses could be raw material for inner evolution

(PhysOrg.com) -- A growing body of evidence underscores the importance of human gut bacteria in modulating human health, metabolism, and disease. Yet bacteria are only part of the story. Viruses that infect ...

Biology / Cell & Microbiology

created Mar 19, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Molecular path from internal clock to cells controlling rest and activity revealed in new study

(PhysOrg.com) -- The molecular pathway that carries time-of-day signals from the body's internal clock to ultimately guide daily behavior is like a black box, says Amita Sehgal, PhD, the John Herr Musser Professor ...

Biology / Cell & Microbiology

created Feb 07, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Tracing an elusive killer parasite in Peru

Despite what Hollywood would have you believe, not all epidemics involve people suffering from zombie-like symptoms--some can only be uncovered through door-to-door epidemiology and advanced mathematics.

Biology / Other

created Sep 27, 2011 | popularity 4.4 / 5 (7) | comments 2 | with audio podcast

Gatekeepers: Study discovers how microbes make it past tight spaces between cells

There are ten microbial cells for every one human cell in the body, and microbiology dogma holds that there is a tight barrier protecting the inside of the body from outside invaders, in this case bacteria. ...

Biology / Cell & Microbiology

created Jun 16, 2011 | popularity not rated yet | comments 0

'Wrong'-time eating reduces fertility in fruit flies

Dieticians will tell you it isn't healthy to eat late at night: it's a recipe for weight gain. In fruit flies, at least, there's another consequence: reduced fertility.

Biology / Cell & Microbiology

created Jun 07, 2011 | popularity not rated yet | comments 1

Predicting the fate of personalized cells next step toward new therapies

Discovering the step-by-step details of the path embryonic cells take to develop into their final tissue type is the clinical goal of many stem cell biologists. To that end, Kenneth S. Zaret, PhD, professor ...

Biology / Cell & Microbiology

created May 19, 2011 | popularity not rated yet | comments 1 | with audio podcast

Ends of chromosomes protected by stacked, coiled DNA caps, study finds

(PhysOrg.com) -- Researchers at the University of Pennsylvania School of Medicine are delving into the details of the complex structure at the ends of chromosomes. Recent work, e-published in Nature Structural & ...

Biology / Cell & Microbiology

created Apr 20, 2011 | popularity 4.5 / 5 (2) | comments 4 | with audio podcast

A new way to make reprogrammed stem cells

Researchers at the University of Pennsylvania School of Medicine have devised a totally new and far more efficient way of generating induced pluripotent stem cells (iPSCs), immature cells that are able to ...

Biology / Cell & Microbiology

created Apr 07, 2011 | popularity 5 / 5 (8) | comments 2 | with audio podcast

Opioids now most prescribed class of medications

Two reports by addiction researchers at the University of Pennsylvania School of Medicine and the National Institute on Drug Abuse show a drastic shift in prescribing patterns impacting the magnitude of opioid substance abuse ...

Medicine & Health / Medications

created Apr 05, 2011 | popularity not rated yet | comments 0

Modern targeted drug plus old malaria pill serve a 1-2 punch in advanced cancer patients

Researchers at the University of Pennsylvania School of Medicine may have found a way to turn an adaptive cellular response into a liability for cancer cells. When normal cells are starved for food, they chew up existing ...

Medicine & Health / Cancer

created Apr 05, 2011 | popularity 4 / 5 (1) | comments 1

Study sheds light on end of life management of implanted defibrillators

Each year, more than 100,000 patients in the U.S. undergo implantation of a new implantable cardioverter defibrillator (ICD) for heart rhythm abnormalities. This number constitutes a 20-fold increase over the last 15 years. ...

Medicine & Health / Other

created Apr 05, 2011 | popularity not rated yet | comments 0

Transcatheter aortic valve implantation as good as traditional surgery for high risk, operable patients

Just released data from a clinical trial shows continued promise for a new minimally invasive treatment option for patients with severe aortic stenosis. New research presented at the 2011 American College ...

Medicine & Health / Other

created Apr 05, 2011 | popularity 3 / 5 (1) | comments 0

Severe psoriasis linked to major adverse cardiovascular events

Psoriasis is a common inflammatory skin disease, and if severe, has been demonstrated to be a risk factor for cardiovascular (CV) disease. However, the degree to which psoriasis is associated with major adverse cardiac events ...

Medicine & Health / Diseases, Conditions, Syndromes

created Apr 04, 2011 | popularity 5 / 5 (1) | comments 0

Cardiovascular patients' perspectives on guilt as a motivational tool

Current research supports the notion that lifestyle choices influence cardiovascular health, but to what extent specific emotions play is undefined. Now, new research from the University of Pennsylvania School of Medicine ...

Medicine & Health / Other

created Apr 04, 2011 | popularity not rated yet | comments 0

Study suggests another avenue for detecting Alzheimer's disease

Researchers at the University of Pennsylvania School of Medicine have determined that a well-known chemical process called acetylation has a previously unrecognized association with one of the biological processes ...

Medicine & Health / Medical research

created Apr 01, 2011 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast