University of Pennsylvania School of Medicine

Low-fat diet helps genetically predisposed animals avoid liver cancer

In a study comparing two strains of mice, one susceptible to developing cancer and the other not, researchers found that a high-fat diet predisposed the cancer-susceptible strain to liver cancer, and that by switching to ...

Medicine & Health / Genetics

created Jun 12, 2009 | popularity not rated yet | comments 1

Researchers discover genetic risk factor for testicular cancer

Researchers at the University of Pennsylvania School of Medicine have uncovered variation around two genes that are associated with an increased risk of testicular cancer. Testicular cancer is the most common cancer among ...

Medicine & Health / Genetics

created May 31, 2009 | popularity not rated yet | comments 1

Compliance and cost: Bitter pills to swallow in the age of oral chemotherapy

Though the growing shift toward oral chemotherapy agents offers cancer patients greater freedom and independence during their treatment, physicians say use of the new medications also poses more chances for patients to skip ...

Medicine & Health / Cancer

created May 28, 2009 | popularity not rated yet | comments 0

Protein predicts development of invasive breast cancer in women with DCIS

Women with ductal carcinoma in situ (DCIS) who exhibit an overexpression of the protein HER2/neu have a six-fold increase in risk of invasive breast cancer, according to a new study from the University of Pennsylvania School ...

Medicine & Health / Cancer

created May 22, 2009 | popularity not rated yet | comments 0

Women with chest pain less likely then men to get proper treatment from paramedics

Women with chest pain are less likely than male patients to receive recommended, proven therapies while en route to the hospital, according to new research from the University of Pennsylvania School of Medicine. Despite evidence ...

Medicine & Health / Other

created May 15, 2009 | popularity not rated yet | comments 1

Long-term study results validate efficacy of CT scans for chest pain diagnosis

The first long-term study following a large number of chest pain patients who are screened with coronary computerized tomographic angiography (CTA) confirms that the test is a safe, effective way to rule out serious cardiovascular ...

Medicine & Health / Other

created May 15, 2009 | popularity not rated yet | comments 0

New Target for Maintaining Healthy Blood Pressure Discovered

(PhysOrg.com) -- In trying to understand the role of prostaglandins - a family of fatty compounds key to the cardiovascular system - in blood pressure maintenance, researchers at the University of Pennsylvania ...

Medicine & Health / Medical research

created Apr 24, 2009 | popularity 4.2 / 5 (5) | comments 0

First noninvasive technique to accurately predict mutations in human brain tumors

Donald O'Rourke, MD, Associate Professor of Neurosurgery at the University of Pennsylvania School of Medicine and colleagues, were able to accurately predict the specific genetic mutation that caused brain cancer in a group ...

Medicine & Health / Cancer

created Apr 20, 2009 | popularity not rated yet | comments 0

Penn's online survivorship care plans empower cancer survivors, caregivers

An online tool that provides cancer survivors and their family members with an easy-to-follow roadmap for managing their health as they finish treatment and transition to life as a survivor got high marks from users, according ...

Medicine & Health / Cancer

created Apr 19, 2009 | popularity not rated yet | comments 0

Scientists use RNA to reprogram one cell type into another

(PhysOrg.com) -- For the past decade, researchers have tried to tweak cells at the gene and nucleus level to reprogram their identity. Now, working on the idea that the signature of a cell is defined by molecules ...

Biology / Cell & Microbiology

created Apr 16, 2009 | popularity 5 / 5 (2) | comments 0

Locking Parasites in Host Cell Could Be New Way to Fight Malaria, Penn Study Shows

(PhysOrg.com) -- Researchers at the University of Pennsylvania have discovered that parasites hijack host-cell proteins to ensure their survival and proliferation, suggesting new ways to control the diseases ...

Biology / Cell & Microbiology

created Apr 04, 2009 | popularity 5 / 5 (4) | comments 1

Women with breast cancer family history may cut their risk through regular workout

A new federally funded University of Pennsylvania School of Medicine study aims to learn whether women at high risk of breast cancer can use exercise to meaningfully reduce their risk of getting the disease. Building on evidence ...

Medicine & Health / Cancer

created Apr 02, 2009 | popularity not rated yet | comments 1

Questioning why health care IT manufacturers aren't liable for product-related medical errors

Even when their products are implicated in harm to patients, manufacturers of healthcare information technology (HIT) currently enjoy wide contractual and legal protection that renders them virtually "liability-free," writes ...

Medicine & Health / Other

created Mar 25, 2009 | popularity not rated yet | comments 0

Proteins by design: Biochemists create new protein from scratch

(PhysOrg.com) -- No doubt proteins are complex. Most are "large" and full of interdependent branches, pockets and bends in their final folded structure. This complexity frustrates biochemists and protein engineers ...

Chemistry / Biochemistry

created Mar 23, 2009 | popularity 5 / 5 (7) | comments 3

Penn medicine draws road map for elimination of central line-associated bloodstream infections

Central line-associated bloodstream infections (CLABSI) fell by more than 90 percent during the past three years at the Hospital of the University of Pennsylvania due to a multi-pronged approach combining leadership initiatives, ...

Medicine & Health / Diseases, Conditions, Syndromes

created Mar 20, 2009 | popularity not rated yet | comments 0