Scientists use CRISPR to discover Zika and dengue weaknesses

Scientists at the University of Massachusetts Medical School (UMMS) have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work, led by Abraham Brass, MD, PhD, assistant ...

Novel technology vastly improves CRISPR/Cas9 accuracy

A new CRISPR/Cas9 technology developed by scientists at the University of Massachusetts Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target ...

Living longer, not healthier

A study of long-lived mutant C. elegans by scientists at the University of Massachusetts Medical School shows that the genetically altered worms spend a greater portion of their life in a frail state and exhibit less activity ...

Tuning light to kill deep cancer tumors

An international group of scientists led by Gang Han, PhD, at the University of Massachusetts Medical School, has combined a new type of nanoparticle with an FDA-approved photodynamic therapy to effectively kill deep-set ...

Researchers show fruit flies have latent bioluminescence

New research from Stephen C. Miller, PhD, associate professor of biochemistry and molecular pharmacology, shows that fruit flies are secretly harboring the biochemistry needed to glow in the dark—otherwise known as bioluminescence.

Vitamin B12 accelerates worm development

Everyday our cells take in nutrients from food and convert them into the building blocks that make life possible. However, it has been challenging to pinpoint exactly how a single nutrient or vitamin changes gene expression ...

Scientists re-imagine how genomes are assembled

Scientists at the University of Massachusetts Medical School (UMMS) have developed a new method for piecing together the short DNA reads produced by next-generation sequencing technologies that are the basis for building ...

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