Genetic traffic signal orchestrates early embryonic development

You are the product of metamorphosis. During the third week of your embryonic existence, fateful genetic choices were made that began to transform a tiny ball of identical stem cells into a complex organism of flesh and blood, ...

When poverty becomes disease

Talmadge King Jr., MD, dean of the UCSF School of Medicine, tells the story of an ER physician who had lost a document and was searching frantically for it in the garbage bins behind Zuckerberg San Francisco General Hospital ...

Researchers create cellular 'ORACLs' to aid drug discovery

A team of researchers at UC San Francisco has devised a new approach for early stage drug discovery that uses techniques from the world of computer vision in combination with a powerful new tool: a lineage of genetically ...

Sensory illusion causes cells to self-destruct

Magic tricks work because they take advantage of the brain's sensory assumptions, tricking audiences into seeing phantoms or overlooking sleights of hand. Now a team of UC San Francisco researchers has discovered that even ...

Human gene prevents regeneration in zebrafish

Regenerative medicine could one day allow physicians to correct congenital deformities, regrow damaged fingers, or even mend a broken heart. But to do it, they will have to reckon with the body's own anti-cancer security ...

Three ways viruses have changed science for the better

A virus is nature's efficient little killer. It can invade a cell, take over its inner machinery, trick it into making more virus DNA and escape with a new posse of virus children (often killing the host in the process). ...

Portable, rapid DNA test can detect Ebola and other pathogens

Using technical advances not yet developed when the 2014 Ebola outbreak began, UC San Francisco-led scientists completed a proof-of-principle study on a real-time blood test based on DNA sequencing that can be used to rapidly ...

Shouldering the burden of evolution

As early humans increasingly left forests and utilized tools, they took an evolutionary step away from apes. But what this last common ancestor with apes looked like has remained unclear. A new study led by researchers at ...

Researchers unveil DNA-guided 3-D printing of human tissue

A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These ...

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