UC San Francisco researchers have discovered a way to switch off the widely used CRISPR-Cas9 gene-editing system using newly identified anti-CRISPR proteins that are produced by bacterial viruses. The technique has the potential ...
Biotechnology
Dec 29, 2016
0
1199
Researchers from UC San Francisco and the Broad Institute of MIT and Harvard have developed a new method for performing high-throughput functional screening of complex genetic interactions and resulting phenotypes in single ...
Biotechnology
Dec 16, 2016
0
25
In a developing embryo, some cells can self-segregate – like oil separating out of water – to help create the tissues and organs of the human body. For example, brain cells separate into clusters that give rise to different ...
Cell & Microbiology
Oct 20, 2016
0
4
Two hundred miles above Earth, NASA has conducted the first genome sequencing in space, and researchers at UC San Francisco helped analyze the data sent back from the International Space Station and confirm that the process ...
Space Exploration
Aug 31, 2016
0
1770
Popular theories of why our human ancestors gained and then lost dark skin over the course of evolution may be incorrect, according to a new paper by UC San Francisco authors, who suggest that heavily pigmented skin evolved ...
Evolution
Jun 27, 2016
0
96
When your dentist injects lidocaine into your gums, the drug blocks the pain of the oncoming drill, but it also blocks all other sensation – leaving your mouth feeling numb and swollen. What if there were a drug that could ...
Biochemistry
Jun 7, 2016
1
15
A research team led by UC San Francisco scientists has discovered a cellular signaling system that regulates the virulence of Cryptococcus neoformans, a fungus that has been estimated to cause nearly a million cases of meningitis ...
Cell & Microbiology
Jun 6, 2016
0
540
Researchers at UC San Francisco and Stanford University have performed the first comprehensive survey of the central genes and proteins essential to bacterial life. The study, which combined a new variant of CRISPR gene-editing ...
Cell & Microbiology
May 27, 2016
0
18
A team of cancer researchers led by scientists at UC San Francisco and Memorial Sloan Kettering Cancer Center demonstrated in human cells and mouse models that a first-of-its-kind hybrid drug can outsmart drug-resistant cancers.
Biochemistry
May 25, 2016
0
100
New research by UCSF scientists could accelerate – by 10 to 100-fold – the pace of many efforts to profile gene activity, ranging from basic research into how to build new tissues from stem cells to clinical efforts to ...
Biotechnology
Apr 28, 2016
0
49
