The Wistar Institute is a biomedical center, with a focus on cancer research and vaccine development. It is located in the University City section of Philadelphia, Pa. Founded in 1892 as the first independent, nonprofit, biomedical research institute in the country, Wistar has held the Cancer Center designation from the National Cancer Institute since 1972. Wistar has more than thirty laboratories, which are home to three research programs: a gene expression and regulation program, a molecular and cellular oncogenesis program, and an immunology program. The Institute's research program on cancer includes the following goals and areas: Wistar's training and outreach initiatives include: The Wistar Institute was founded in 1892 as the nation’s first independent medical research facility. It is named for Caspar Wistar, M.D., a prominent Philadelphia physician who began his medical practice in 1787. Dr. Wistar was the author of the first American anatomy textbook. To augment his medical lectures and illustrate comparative anatomy, Dr. Wistar began a collection of dried, wax-injected, and preserved human specimens.
It slices, it dices, it silences: ADAR1 as gene-silencing modular RNA multitool
RNA, once considered a bit player in the grand scheme by which genes encode protein, is increasingly seen to have a major role in human genetics. In a study presented in the April 25 issue of the journal Cell, researchers from T ...
'Activating' RNA takes DNA on a loop through time and space
Long segments of RNA—encoded in our DNA but not translated into protein—are key to physically manipulating DNA in order to activate certain genes, say researchers at The Wistar Institute. These non-coding RNA-activators ...
It takes two to tangle: Scientists further unravel telomere biology
Chromosomes - long, linear DNA molecules – are capped at their ends with special DNA structures called telomeres and an assortment of proteins, which together act as a protective sheath. Telomeres are maintained through ...