The Scripps Research Institute (TSRI) is a biomedical research corporation established in La Jolla, California with another site in Jupiter, Florida. Its origins stem from a large endowment from Ellen Browning Scripps in the 1920s originally targeted for research on immune disorders. In the 1990s the combined Scripps Clinic and Research Institute became separate entitities. Today, TSRI is one of the most prolific and active research institutes in the United States with a wide range of human disorders/conditions in its focus. Namely, cancer biology, cell therapy, genetics, molecular and experimental medicine, neurobiology and more. The newly constructed Scripps Florida focuses on drug discoveries, basic biomedical research and technologies.
New research led by scientists at The Scripps Research Institute (TSRI) reveals that a human enzyme has changed little from its days as a bacterial enzyme. In fact, the enzyme appears to be unique in its ability to change ...
Scientists at The Scripps Research Institute (TSRI) have developed a vaccine that blocks the pain-numbing effects of the opioid drugs oxycodone (oxy) and hydrocodone (hydro) in animal models. The vaccine also appears to decrease ...
While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem. Side effects, including an increased risk of uterine cancer among postmenopausal ...
A new study led by scientists at The Scripps Research Institute (TSRI) reveals that a protein first discovered at TSRI in 2010 is directly responsible for sensing touch.
Scientists at The Scripps Research Institute (TSRI) have developed a broadly useful method to unmask new functional features of human proteins.
A new study led by scientists at The Scripps Research Institute (TSRI) offers a twist on a popular theory for how life on Earth began about four billion years ago.
Scientists at The Scripps Research Institute (TSRI) have brought physics and biology together to further understand how cells' crowded surfaces induce complex protein behavior.
Chemists at The Scripps Research Institute (TSRI) have invented a new technique for constructing one-handed or "chiral" drug molecules. The new method is already being adopted by pharmaceutical researchers.
A well-known family of natural compounds, called "terpenoids," have a curious evolutionary origin. In particular, one question relevant to future drug discovery has puzzled scientists: exactly how does Nature make these molecules?
Scientists at The Scripps Research Institute (TSRI) have taken a big step toward the laboratory re-creation of the "RNA world," which is generally believed to have preceded modern life forms based on DNA and proteins.