A collaborative study by researchers at the Salk Institute for Biological Studies uncovered that the tumor suppressor p53, which made its name as "guardian of the genome", not only stops cells that could become ...
Aug 09, 2009
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Rather than sticking to a single DNA script, human brain cells harbor astonishing genomic variability, according to scientists at the Salk Institute for Biological Studies. The findings, to be published in ...
Aug 05, 2009
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Just like a conductor cueing musicians in an orchestra, Fgf10, a member of the fibroblast growth factor (Ffg) family of morphogens, lets brain stem cells know that the moment to get to work has arrived, ensuring ...
Jul 15, 2009
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Although the fact that we generate new brain cells throughout life is no longer disputed, their purpose has been the topic of much debate. Now, an international collaboration of researchers made a big leap ...
Jul 09, 2009
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A tightly controlled system of checks and balances ensures that a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn't wreak havoc in healthy cells. In their latest study, ...
Jul 06, 2009
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Alcohol's inebriating effects are familiar to everyone. But the molecular details of alcohol's impact on brain activity remain a mystery. A new study by researchers at the Salk Institute for Biological Studies ...
Jun 28, 2009
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Experiment after experiment confirms that a diet on the brink of starvation expands lifespan in mice and many other species. But the molecular mechanism that links nutrition and survival is still poorly understood. ...
Jun 24, 2009
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Obesity is probably the most important factor in the development of insulin resistance, but science's understanding of the chain of events is still spotty. Now, researchers at the Salk Institute for Biological ...
Jun 21, 2009
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People who suffer from Peutz-Jeghers syndrome, a rare inherited cancer syndrome, develop gastrointestinal polyps and are predisposed to colon cancer and other tumor types. Carefully tracing the cellular chain-of-command ...
Jun 16, 2009
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A study led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic disease can be cured ...
May 31, 2009
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Our genome is a patchwork of neighborhoods that couldn't be more different: Some areas are hustling and bustling with gene activity, while others are sparsely populated and in perpetual lock-down. Breaking ...
May 14, 2009
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New research at the Salk Institute for Biological Studies casts the role of a neuronal growth factor receptor—long suspected to facilitate the toxic effects of beta amyloid in Alzheimer's disease— in a ...
Apr 20, 2009
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About 1.25 million neurons in the retina -- each of which views the world only through a small jagged window called a receptive field -- collectively form the seamless picture we rely on to navigate our environment. ...
Apr 07, 2009
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The visual system has limited capacity and cannot process everything that falls onto the retina. Instead, the brain relies on attention to bring salient details into focus and filter out background clutter. ...
Mar 25, 2009
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A receptor for glutamate, the most prominent neurotransmitter in the brain, plays a key role in the process of "unlearning," report researchers at the Salk Institute for Biological Studies. Their findings, published in the ...
Mar 24, 2009
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