Stressed out: Scientist details cells' response to lesions

In a recent review paper published in Nature Structural & Molecular Biology, SLU scientist Alessandro Vindigni, Ph.D., describes the strategies cells use when their DNA faces replication stress, challenges that may derail ...

Scientist helps move structural biology into 'big data' era

In a recent paper published in Nature Communications, structural biologists detailed how a new data sharing consortium is helping scientists more quickly share and benefit from findings in their field.

High fidelity: Researcher finds keys to genome integrity

Maintaining the stability and the correct sequence of our genetic information is vital to the accurate transmission of our genetic code. However, in the course of replicating, our DNA frequently runs into roadblocks, arising ...

Study discovers a way to control internal clocks

Researchers hypothesize that targeting components of the mammalian clock with small molecules like REV-ERB drugs may lead to new treatments for sleep disorders and anxiety disorders. It also is possible that REV-ERB drugs ...

Trapped: Cell-invading piece of virus captured in lab

In recent research published in the Journal of Biological Chemistry, Saint Louis University investigators report catching integrase, the part of retroviruses like HIV that is responsible for insertion of the viral DNA into ...

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