Rockefeller University

Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of ...

Dec 29, 2008
5 / 5 (4) 0

FHL1 helps build muscle mass

Cowling et al. report how to build muscle mass with FHL1. The protein partners with and activates the transcription factor, NFATc1. Encouraging this partnership might provide a possible treatment for muscle ...

Dec 15, 2008
2.5 / 5 (2) 0

What makes an axon an axon?

Inside every axon is a dendrite waiting to get out. Hedstrom et al. converted mature axons into dendrites by banishing a protein crucial for neuron development. The results suggest that this transformation could occur after ...

Nov 10, 2008
4.5 / 5 (2) 1

Researchers find new path to antibiotics in dirt

(PhysOrg.com) -- A teaspoon of dirt contains an estimated 10,000 species of bacteria, but it’s only one percent of these microbial bugs — the ones that can be grown easily in a lab — that have brought us antibiotics, ...

Nov 07, 2008
4.9 / 5 (8) 0

Without glial cells, animals lose their senses

(PhysOrg.com) -- Sensory neurons have always put on a good show. But now, it turns out, they'll be sharing the credit. In groundbreaking research to appear in the October 31 issue of Science, Rockefeller Univer ...

Oct 30, 2008
4.7 / 5 (9) 0

In mice, anxiety is linked to immune system

(PhysOrg.com) -- In the first study ever to genetically link the immune system to normal behavior, scientists at Rockefeller and Columbia universities show that mast cells, known as the pharmacologic bombshells of the immune ...

Oct 27, 2008
4.2 / 5 (13) 1

Molecule stops DNA replication in its tracks

(PhysOrg.com) -- When a dividing cell duplicates its genetic material, a molecular machine called a sliding clamp travels along the DNA double helix, tethering the proteins that perform the replication. Researchers ...

Oct 20, 2008
4 / 5 (3) 0