Rockefeller University

New nucleotide could revolutionize epigenetics

Anyone who studied a little genetics in high school has heard of adenine, thymine, guanine and cytosine - the A,T,G and C that make up the DNA code. But those are not the whole story. The rise of epigenetics in the past decade ...

Apr 16, 2009
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HIV pays a price for invisibility

Mutations that help HIV hide from the immune system undermine the virus's ability to replicate, show an international team of researchers in the April 13 issue of the Journal of Experimental Medicine. The study was publis ...

Apr 13, 2009
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Research defines dendritic cell lineage

(PhysOrg.com) -- Dendritic cells were discovered more than 30 years ago, but their pedigree has never been fully charted. They were known to be key immune system cells born in bone marrow, but their adolescence remained a ...

Mar 19, 2009
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Turn back, wayward axon

To a growing axon, the protein RGMa is a "Wrong Way" sign, alerting it to head in another direction. As Hata et al. demonstrate in the March 9, 2009 issue of the Journal of Cell Biology, translating that s ...

Mar 09, 2009
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Researchers unveil new monkey model for HIV

By altering just one gene in HIV-1, scientists have succeeded in infecting pig-tailed macaque monkeys with a human version of the virus that has until now been impossible to study directly in animals. The new strain of HIV ...

Mar 02, 2009
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Gene linked to anxious behavior in mice

(PhysOrg.com) -- To measure anxiety in a mouse and suggest it’s similar to anxiety in a person may seem like a stretch, but the metrics sound uncannily familiar. Paralyzed by fear, afraid to leave the house or socialize ...

Feb 19, 2009
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'Birth control' for centrioles

Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that ...

Jan 26, 2009
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