Rockefeller University

Turn back, wayward axon

To a growing axon, the protein RGMa is a "Wrong Way" sign, alerting it to head in another direction. As Hata et al. demonstrate in the March 9, 2009 issue of the Journal of Cell Biology, translating that s ...

Mar 09, 2009
4.5 / 5 (2) 0

Researchers unveil new monkey model for HIV

By altering just one gene in HIV-1, scientists have succeeded in infecting pig-tailed macaque monkeys with a human version of the virus that has until now been impossible to study directly in animals. The new strain of HIV ...

Mar 02, 2009
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Gene linked to anxious behavior in mice

(PhysOrg.com) -- To measure anxiety in a mouse and suggest it’s similar to anxiety in a person may seem like a stretch, but the metrics sound uncannily familiar. Paralyzed by fear, afraid to leave the house or socialize ...

Feb 19, 2009
4.8 / 5 (5) 0

'Birth control' for centrioles

Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that ...

Jan 26, 2009
4 / 5 (2) 0

Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of ...

Dec 29, 2008
5 / 5 (4) 0

FHL1 helps build muscle mass

Cowling et al. report how to build muscle mass with FHL1. The protein partners with and activates the transcription factor, NFATc1. Encouraging this partnership might provide a possible treatment for muscle ...

Dec 15, 2008
2.5 / 5 (2) 0