Rockefeller University

Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology.

dateDec 29, 2008 in
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TWEAK triggers atrophy of disused muscle

A new study in the Journal of Cell Biology (JCB) identifies a cytokine signaling pathway that induces the breakdown of disused skeletal muscle. Blocking this pathway could prevent immobilized patients from losing their muscle ...

dateMar 22, 2010 in Medical research
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Plant virus spreads by making life easy for crop pests

( -- In 752, Japanese Empress Koken wrote a short poem about the summertime yellowing of a field in what is thought to be the first account of a viral plant disease. More than 1,250 years later, scientists concluded ...

dateOct 30, 2008 in
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'Birth control' for centrioles

Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that spurs the organelles' ...

dateJan 26, 2009 in
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