Rockefeller University

How neuronal activity leads to Alzheimer's protein cleavage

Amyloid precursor protein (APP), whose cleavage product, amyloid-b (Ab), builds up into fibrous plaques in the brains of Alzheimer's disease patients, jumps from one specialized membrane microdomain to another to be cleaved, ...

Oct 20, 2008
4.7 / 5 (3) 0

Centromeres cross over, a lot

Recombination at centromeres is higher than anywhere else on the chromosome, even though methyltransferases do their best to prevent it, say Jaco et al., as published in the June 16 issue of the Journal of Cell Biology.

Jun 12, 2008
4.3 / 5 (3) 0

New study bolsters beliefs about DNA repair

Aucott et al. report the first in vivo experiments on the heterochromatin protein 1 (HP1) family, which sidles up to silent DNA. The results, to be published in the Nov. 17 issue of the Journal of Cell Biology, add to the ...

Nov 17, 2008
4.3 / 5 (3) 0