How sperm get into the zona

Before it can fertilize an egg, a sperm has to bind to and bore through an outer egg layer known as the zona pellucida. Despite decades of research, some of the biological mechanisms behind this process remain unclear. A ...

Stem cell progeny tell their parents when to turn on

(Phys.org) —Stem cells switch off and on, sometimes dividing to produce progeny cells and sometimes resting. But scientists don't fully understand what causes the cells to toggle between active and quiet states.

Friction harnessed by proteins helps organize cell division

(Phys.org) —A football-shaped structure, known as the mitotic spindle, makes cell division possible for many living things. This piece of cellular architecture, responsible for dividing up genetic material, is in constant ...

Genetically identical ants help unlock the secrets of larval fate

(Phys.org) —A young animal's genes are not the only genes that determine its fate. The genetic identity of its caretakers matters too. Researchers suspect the interaction between the two can sway the fate of the young animal, ...

Multiple sensory cues draw mosquitoes to hosts

It may seem like mosquitoes will bite anything with a pulse, but they're actually quite strategic in picking their victims. A new study from The Rockefeller University looked at the interaction of different sensory cues—carbon ...

Aging cells unravel their DNA

Senescent cells, which are metabolically active but no longer capable of dividing, contribute to aging, and senescence is a key mechanism for preventing the spread of cancer cells. A study in The Journal of Cell Biology identifies ...

Mutant mosquitoes lose their appetite for humans

(Phys.org) —What draws a mosquito to bite its host has long been studied from the perspective of the victim—uncovering which smells and chemicals lure the insect in. But researchers at Rockefeller's Laboratory of Neurogenetics ...

Scientists discover new way protein degradation is regulated

(Phys.org) —Proteins, unlike diamonds, aren't forever. And when they wear out, they need to be degraded in the cell back into amino acids, where they will be recycled into new proteins. Researchers at Rockefeller University ...

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