Massachusetts General Hospital

Researchers discover cellular system for detecting and responding to poisons and pathogens

Two Massachusetts General Hospital (MGH)-based research teams, along with a group from the University of California at San Diego, have discovered that animals have a previously unknown system for detecting and responding ...

Biology / Cell & Microbiology

created Apr 12, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Rapid method of assembling new gene-editing tool could revolutionize genetic research

Development of a new way to make a powerful tool for altering gene sequences should greatly increase the ability of researchers to knock out or otherwise alter the expression of any gene they are studying. The new method ...

Biology / Biotechnology

created Apr 09, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines

Combining two strategies designed to improve the results of cancer treatment – antiangiogenesis drugs and nanomedicines – may only be successful if the smallest nanomedicines are used. A new study ...

Nanotechnology / Bio & Medicine

created Apr 09, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Novel technique uses RNA interference to block inflammation

Massachusetts General Hospital (MGH) researchers – along with collaborators from Massachusetts Institute of Technology (MIT) and Alnylam Pharmaceuticals – have found a way to block, in an animal model, the damaging ...

Biology / Biotechnology

created Oct 09, 2011 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Expression of pluripotency-associated gene marks many types of adult stem cells

Investigators at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HSCI) have found that Sox2 – one of the transcription factors used in the conversion of ...

Biology / Cell & Microbiology

created Oct 06, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Single Green Fluorescent Protein-expressing cell is basis of living laser device

(PhysOrg.com) -- It sounds like something out of a comic book or a science fiction movie – a living laser – but that is exactly what two investigators at the Wellman Center for Photomedicine at Massachusetts ...

Physics / Optics & Photonics

created Jun 12, 2011 | popularity 4.9 / 5 (14) | comments 3 | with audio podcast

Alzheimer's-like brain changes found in cognitively normal elders with amyloid plaques

Researchers using two brain-imaging technologies have found that apparently normal older individuals with brain deposits of amyloid beta – the primary constituent of the plaques found in the brains of Alzheimer's disease ...

Medicine & Health / Neuroscience

created Mar 30, 2011 | popularity 5 / 5 (1) | comments 0

Advanced technology reveals activity of single neurons during seizures

The first study to examine the activity of hundreds of individual human brain cells during seizures has found that seizures begin with extremely diverse neuronal activity, contrary to the classic view that they are characterized ...

Medicine & Health / Neuroscience

created Mar 27, 2011 | popularity 4.6 / 5 (7) | comments 1 | with audio podcast

Study reveals how lung cancers evolve in response to targeted treatment

A detailed analysis of lung tumors that became resistant to targeted therapy drugs has revealed two previously unreported resistance mechanisms. In a report in the March 23 Science Translational Medicine, investigators from t ...

Medicine & Health / Cancer

created Mar 23, 2011 | popularity not rated yet | comments 0

Metabolite levels may be able to improve diabetes risk prediction

Measuring the levels of small molecules in the blood may be able to identify individuals at elevated risk of developing type 2 diabetes as much as a decade before symptoms of the disorder appear. In a report receiving advance ...

Medicine & Health / Diseases, Conditions, Syndromes

created Mar 20, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Current projections greatly underestimate impact of Haitian cholera epidemic: study

Current projections regarding the eventual size and extent of the cholera epidemic in Haiti may greatly underestimate the potential number of cases, according to a report that will appear in The Lancet and has been releas ...

Medicine & Health / Diseases, Conditions, Syndromes

created Mar 15, 2011 | popularity 5 / 5 (1) | comments 0

Aspirin's ability to protect against colorectal cancer may depend on inflammatory pathways

The reduced risk of colorectal cancer associated with taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) may be confined to individuals already at risk because of elevations in a particular inflammatory ...

Medicine & Health / Cancer

created Mar 09, 2011 | popularity not rated yet | comments 0

Increased, mandatory screenings help identify more kids with emotional/behavioral problems

A study published in the March 2011 Archives of Pediatrics and Adolescent Medicine shows that Massachusetts' new court-ordered mental health screening and intervention program led to more children being identified as beh ...

Medicine & Health / Health

created Mar 07, 2011 | popularity 4 / 5 (1) | comments 1

International collaborative identifies 13 new heart-disease-associated gene sites

Thirteen new gene regions have been convincingly linked to coronary atherosclerosis in a massive, new, international genetics study involving investigators from the Stanford University School of Medicine.

Medicine & Health / Genetics

created Mar 06, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Brain rhythm predicts real-time sleep stability, may lead to more precise sleep medications

A new study finds that a brain rhythm considered the hallmark of wakefulness not only persists inconspicuously during sleep but also signifies an individual's vulnerability to disturbance by the outside world. In their report ...

Medicine & Health / Medical research

created Mar 03, 2011 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast