Scientists at Johns Hopkins have created a 3-D model of a complex protein machine, ORC, which helps prepare DNA to be duplicated. Like an image of a criminal suspect, the intricate model of ORC has helped build a "profile" ...
Cell & Microbiology
Mar 11, 2015
0
39
Like a surgeon separating conjoined twins, cells have to be careful to get everything just right when they divide in two. Otherwise, the resulting daughter cells could be hobbled, particularly if they end up with too many ...
Cell & Microbiology
Feb 19, 2015
0
66
Just as human relationships are a two-way street, fusion between cells requires two active partners: one to send protrusions into its neighbor, and one to hold its ground and help complete the process. Researchers have now ...
Cell & Microbiology
Feb 12, 2015
0
16
For more than a decade, a vial of rare snake venom refused to give up its secret formula for lethality; its toxins had no effect on the proteins that most venoms target. Finally, an international team of researchers figured ...
Cell & Microbiology
Feb 9, 2015
2
123
Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often ...
Bio & Medicine
Feb 4, 2015
0
82
Organization is key to an efficient workplace, and cells are no exception to this rule. New evidence from Johns Hopkins researchers suggests that, in addition to membranes, cells have another way to keep their contents and ...
Cell & Microbiology
Jan 16, 2015
2
103
For a skin cell to do its job, it must turn on a completely different set of genes than a liver cell—and keep genes it doesn't need switched off. One way of turning off large groups of genes at once is to send them to "time-out" ...
Cell & Microbiology
Jan 6, 2015
0
734
A powerful "genome editing" technology known as CRISPR has been used by researchers since 2012 to trim, disrupt, replace or add to sequences of an organism's DNA. Now, scientists at Johns Hopkins Medicine have shown that ...
Cell & Microbiology
Jan 5, 2015
0
44
Researchers at Johns Hopkins have discovered what keeps an enzyme from becoming overzealous in its clipping of DNA. Since controlled clipping is required for the production of specialized immune system proteins, an understanding ...
Cell & Microbiology
Dec 24, 2014
0
0
Working at the edge of a coal mine in India, a team of Johns Hopkins researchers and colleagues have filled in a major gap in science's understanding of the evolution of a group of animals that includes horses and rhinos. ...
Paleontology & Fossils
Nov 20, 2014
0
0
