The Howard Hughes Medical Institute (HHMI) is headquartered in Chevy Chase, Maryland. HHMI was founded in 1953 and has flourished as the foremost benefactor for basic research in the areas of molecular biology, genetics, immunology and biomedical research. HHMI has a $17.5 billion dollar endowment and yearly awards around $450 million dollars to scientists in university labs involved in scientific pursuits that coincide with industrialists Howard Hughes' goal of discovering the “genesis of life itself”.
Surprise finding: Pancreatic cancers progress to lethal stage slowly
Pancreatic tumors are one of the most lethal cancers, with fewer than five percent of patients surviving five years after diagnosis. But a new study that peers deeply into the genetics of pancreatic cancer presents a bit ...
Genome-wide methylation map of disease-causing E. coli reveals surprises
(Phys.org)—A new DNA sequencing technique has enabled researchers to map for the first time the influential chemical modifications known as methylation marks throughout the genome of a pathogenic bacterium. By comparing ...
Asexual plant reproduction may seed new approach for agriculture
An HHMI scientist has moved a step closer to turning sexually-reproducing plants into asexual reproducers, a finding that could have profound implications for agriculture.
New ways to disarm deadly South American hemorrhagic fever viruses
New World hemorrhagic fevers are emerging infectious diseases found in South America that can cause terrible, Ebola-like symptoms. Current treatments are expensive and only partially effective.
Researchers identify new stem cell
(PhysOrg.com) -- Scientists have discovered a new type of stem cell in the skin that acts surprisingly like certain stem cells found in embryos: both can generate fat, bone, cartilage, and even nerve cells. These newly-described ...
Super-resolution microscopy takes on a third dimension
The shapes of some of the tiniest cellular structures are coming into sharper focus at the Howard Hughes Medical Institute's Janelia Farm Research Campus, where scientists have developed a new imaging technology that produces ...
Researchers identify gene that spurs deadly brain cancer
Howard Hughes Medical Institute (HHMI) researchers have identified a new factor that is necessary for the development of many forms of medulloblastoma, the most common type of malignant childhood brain cancer.
New medications show promise in treating drug-resistant prostate cancer
A new therapy for metastatic prostate cancer has shown considerable promise in early clinical trials involving patients whose disease has become resistant to current drugs.
In India: A search for more effective tuberculosis drugs
Rajesh Gokhale has created a compound in his lab in India that stops tuberculosis in its tracks. In a test tube, the molecule hits four of the bacterium's crucial metabolic pathways at the same time, weakening and ultimately ...
With genomes, bigger may really be better
Biologists analyzing DNA in search of the molecular underpinnings of life have consistently favored species with small genomes, which are cheaper to sequence and lack the repetitive "junk" that clutters bigger genomes. But ...