New insight into Bloom's syndrome
Two independent papers in the October 15th issue of G&D detail the discovery of a previously unidentified fourth component of the Bloom's syndrome complex.
Use it or lose it? Researchers investigate the dispensability of our DNA
Our genome contains many genes encoding proteins that are similar to those of other organisms, suggesting evolutionary relationships; however, protein-coding genes account for only a small fraction the genome, and there are ...
Researchers find an essential gene for forming ears of corn
Scientists trace extensive networks regulating alternative RNA splicing
Interdisciplinary volume on biological rhythms serves as both primer and in-depth resource
Senescence in liver cells can provoke a beneficial immune reaction
Although post-reproductive life in humans is often associated with decline and a loss of powers, an analogous state in certain cells -- called senescence -- is proving to be one of ironic potency. Scientists at Cold Spring ...
Rheb's role in cancer
Two independent papers in the August 15th issue of G&D identify the Rheb GTPase as a novel oncogene and a promising new chemotherapeutic target.
Study shows that laboratory rats calculate confidence to make decisions
It has probably happened to everyone at one time or another. You're driving to a restaurant for the very first time. At a crossroads, you make a turn. You drive for several minutes, and then several minutes more. Nothing ...
Scientists demonstrate means of reducing Alzheimer's-like plaques in fly brain
Neuroscientists at Cold Spring Harbor Laboratory (CSHL) are part of a collaboration that has succeeded in demonstrating that overexpression of an enzyme in the brain can reduce telltale deposits causally linked with Alzheimer's ...
Scientists discover key patterns in the packaging of genes
Although every cell of our bodies contains the same genetic instructions, specific genes typically act only in specific cells at particular times. Other genes are "silenced" in a variety of ways. One mode of gene silencing ...
Scientists identify genetic basis for the black sheep of the family
Neuroscientists show insulin receptor signaling regulates structure of brain circuits
[B]Impact of the signaling upon synapses and dendrites is shown for the first time in living creatures[/B] A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated for the first time in living ani ...
Novel model of osteosarcoma
In the June 15th issue of G&D, Dr. Stuart Orkin (HHMI, Dana-Farber Cancer Institute, Children's Hospital Boston) and colleagues present a new mouse model of osteosarcoma.
Scientists trace causal link between a tumor suppressor gene and liver cancer
Scientists at Cold Spring Harbor Laboratory (CSHL) have taken the search for cancer-causing genes an important step forward. In a newly published paper, they confirm that a gene called DLC1 is a tumor suppressor. They have ...