Cold Spring Harbor Laboratory

Targeting MMPs to halt advanced metastatic breast cancer

An upcoming G&D paper reveals how two specific matrix metalloproteinase (MMP) proteins contribute to bone metastasis in advanced breast cancer - lending important new insight into the design of clinically useful small molecule ...

dateJul 16, 2009 in Cancer
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United we stand; divided we fall

In the July 15th issue of G&D, Dr. Roberto Kolter (Harvard Medical School) and colleagues make the unprecedented observation of paracrine signaling during Bacillus subtilis biofilm formation.

dateJul 15, 2009 in Cell & Microbiology
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MicroRNAs grease the cell's circadian clockwork

Most of our cells possess an internal clock, a group of genes displaying a cyclic expression pattern that reaches a peak once a day. A large number of circadian genes are expressed by organs such as the liver, whose activity ...

dateMay 31, 2009 in Genetics
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Beyond associations: Colorectal cancer culprit found

Genetics plays a key role in determining risk for colorectal cancer, the second leading cause of cancer-related deaths in the United States. Several common genetic markers have been found to be associated with the disease, ...

dateApr 23, 2009 in Cancer
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Lice genomes: Pieces of a new puzzle

Parents and school nurses take note. Lice are a familiar nuisance around the world and vectors of serious diseases, such as epidemic typhus, in developing regions. New research indicates that lice may actually ...

dateMar 30, 2009 in Cell & Microbiology
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