Cincinnati Children's Hospital Medical Center (CCHMC) was founded in 1833 in Cincinnati, Ohio. The hospital medical center is affiliated with the University of Cincinnati. Noteworthy, among CCHMC achievements include, an award for exemplary research in Pediatric care from the National Institutes of Health, consistent funding by the NIH, and is one of the five training centers for pediatric care in the USA.
New research tool tracks real-time DNA-protein binding in cells
Researchers have developed a new technology that precisely marks where groups of regulatory proteins called transcription factors bind DNA in the nuclei of live cells.
Furthering data analysis of next-generation sequencing to facilitate research
Researchers at Cincinnati Children's Hospital Medical Center have developed a user-friendly, integrated platform for analyzing the transcriptomic and epigenomic "big data."
Sci-Fly study explores how lifeforms know to be the right size
Shakespeare said "to be or not to be" is the question, and now scientists are asking how life forms grow to be the correct size with proportional body parts.
Study suggests antioxidant treatment may help NF1-linked behavioral issues
New research in mouse models suggests that treatment with antioxidants may help reduce behavioral issues linked to the genetic nervous system disorder Neurofibromatosis 1 (NF1) and an associated condition called Costello ...
New candidate drug stops cancer cells, regenerates nerve cells
Scientists have developed a small-molecule-inhibiting drug that in early laboratory cell tests stopped breast cancer cells from spreading and also promoted the growth of early nerve cells called neurites.
Fruit flies reveal surprising new evolutionary link for studying human health
New research reveals that fruit flies and mammals may share a surprising evolutionary link in how they control body temperature through circadian rhythm, unlocking new ways to study the insects as models of human development ...
Scientists successfully reprogram blood cells
Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme -preventing or reducing organ and central nervous system damage ...
Stem cells turned into complex, functioning intestinal tissue in lab
For the first time, scientists have created functioning human intestinal tissue in the laboratory from pluripotent stem cells.
Fruit fly study digs deeper into poorly understood details of forming embryos
Using fruit flies as a model to study embryo formation, scientists report in Nature Cell Biology that molecular breakdown of a protein called Bicoid is vital to normal head-to-tail patterning of the insect's offspring.
Novel regulatory process for T cells may help explain immune system diseases
A newly identified regulatory process affecting the biology of immune system T cells should give scientists new approaches to explore the causes of autoimmunity and immune deficiency diseases.