Burnham Institute

Delivering medicine directly into a tumor

Researchers at Burnham Institute for Medical Research at University of California, Santa Barbara have identified a peptide (a chain of amino acids) that specifically recognizes and penetrates cancerous tumors but not normal ...

dateDec 07, 2009 in Cancer
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Building a complete metabolic model

Investigators at Burnham Institute for Medical Research, University of California, San Diego, The Scripps Research Institute, Genomics Institute of the Novartis Research Foundation and other institutions have constructed ...

dateSep 17, 2009 in Cell & Microbiology
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Reactive oxygen's role in metastasis

Researchers at the Burnham Institute for Medical Research have discovered that reactive oxygen species, such as superoxide and hydrogen peroxide, play a key role in forming invadopodia, cellular protrusions implicated in ...

dateSep 16, 2009 in Cancer
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New insights into cardiac aging

Investigators at Burnham Institute for Medical Research (Burnham) have found that the conserved protein d4eBP modulates cardiac aging in Drosophila (fruit flies). The team also found that d4eBP, which binds to the protein ...

dateSep 14, 2009 in Medical research
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When proteins change partners

Dieter Wolf, M.D., and colleagues at Burnham Institute for Medical Research (Burnham) have illuminated how competition between proteins enhances combinatorial diversity during ubiquitination (the process that marks proteins ...

dateSep 11, 2009 in Biochemistry
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New insights into limb formation

Investigators at Burnham Institute for Medical Research (Burnham) and the University of Connecticut Health Center (U.C.H.C.) have gained new understanding of the role hyaluronic acid (HA) plays in skeletal growth, chondrocyte ...

dateAug 12, 2009 in Medical research
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What makes stem cells tick?

Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...

dateAug 06, 2009 in Cell & Microbiology
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Unraveling how cells respond to low oxygen

Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, ...

dateAug 05, 2009 in Medical research
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Protein that promotes cancer cell growth identified

Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer ...

dateJul 24, 2009 in Cancer
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Carbohydrate acts as tumor suppressor

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specialized complex sugar molecules (glycans) that anchor cells into place act as tumor suppressors in breast and prostate cancers. These ...

dateJul 06, 2009 in Cancer
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MicroRNAs help control HIV life cycle

Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. In particular, ...

dateJun 25, 2009 in Biochemistry
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