A team of scientists at Whitehead Institute and the Broad Institute of MIT and Harvard have systematically evaluated the functions of more than 5,000 essential human genes using a novel, pooled, imaged-based screening method. ...
Cell & Microbiology
Nov 8, 2022
0
209
Copy number variants (CNVs) are regions of the genome that are duplicated or deleted in some individuals, and are a common type of gene-disabling mutation. The human genome contains hundreds of thousands of CNVs, but typical ...
Cell & Microbiology
Oct 28, 2022
0
58
Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest ...
Biotechnology
Oct 27, 2022
0
39
Cyclosporine is one of the most common and effective immunosuppressant drugs used to treat chronic diseases like arthritis and psoriasis, but it comes with a risk of serious side effects. Scientists think that may be because ...
Biochemistry
Sep 27, 2022
0
84
Scientists have learned a lot about human biology by looking at cells under a microscope, but they might not notice tiny differences between cells or even know what they're looking for. Researchers at the Broad Institute ...
Cell & Microbiology
Aug 3, 2022
0
26
Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need to know where they are ...
Cell & Microbiology
May 12, 2022
0
121
Copper is an essential element of life from bacteria and fungi to plants and animals. In humans, it binds to enzymes to help blood clot, hormones mature, and cells process energy. But too much copper kills cells—and now ...
Cell & Microbiology
Mar 18, 2022
0
367
Researchers have developed an automated method that predicts the effectiveness of viral diagnostic tests and designs optimized ones.
Biotechnology
Mar 4, 2022
0
51
Gene editing approaches promise to treat a range of diseases, but delivering editing agents to cells in animal models and humans safely and efficiently has proven challenging. Now, researchers led by a team at the Broad Institute ...
Cell & Microbiology
Jan 12, 2022
0
111
Within complex tissues such as cancer tumors, individual cells can vary widely from each other. Internally, cancer cells can develop unique DNA mutations and genomic changes, potentially leading to drug resistance, metastasis, ...
Cell & Microbiology
Dec 16, 2021
0
94
