Tissue engineered scaffolding allows reproduction of cartilage tissue

May 09, 2007

A new study examines the use of tissue-engineered scaffolding made of cartilage cells, which have a limited ability to heal naturally, to replace defective cartilage tissue. Cartilage cells are extracted and seeded to the scaffold which is implanted into the body, where new cartilage tissue is grown along the structure. The study appears in the journal Artificial Organs.

The procedure was extremely successful in tested mice as the study found these scaffolds to be a far more effective means of regenerating cartilage than traditional therapy. The shrinkage of cartilage that occurs frequently in other tissue engineering methods, and often renders the replacement tissue wrongly-sized for implantation, did not occur in the study. The scaffolding allowed the newly grown cartilage to maintain its volume during cultivation and post-procedure.

"The cell-derived scaffold could provide a favorable environment for cartilage cells to maintain their characteristics while synthesizing cartilage in the scaffold structure in vivo," notes study author Dr. Byoung-Hyun Min. "Cell-derived scaffolding may hold great promise for the future. A variety of applications are possible for the engineering of cartilage tissue as the shape and porosity can be altered to suit the type of tissue required."

Source: Blackwell Publishing Ltd.

Explore further: Investigators show how immune cells are 'educated' not to attack beneficial bacteria

Related Stories

Researchers use silk to cultivate organ tissues in the lab

Apr 02, 2015

Few organs in the body are as complicated as the human brain, a tight spiderweb of neurons that shoots electrical signals across synapses to control all our thoughts and movements. When something goes wrong—as ...

New method to grow synthetic collagen unveiled

Sep 08, 2011

In a significant advance for cosmetic and reconstructive medicine, scientists at Rice University have unveiled a new method for making synthetic collagen. The new material, which forms from a liquid in as ...

Recommended for you

Fat signals control energy levels in the brain

Apr 23, 2015

An enzyme secreted by the body's fat tissue controls energy levels in the brain, according to new research at Washington University School of Medicine in St. Louis. The findings, in mice, underscore a role ...

Human tape worm drug shows promise against MRSA in lab

Apr 23, 2015

A new study provides evidence from lab experiments that a drug already used in people to fight tapeworms might also prove effective against strains of the superbug MRSA, which kills thousands of people a ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.