Tissue engineered scaffolding allows reproduction of cartilage tissue

May 09, 2007

A new study examines the use of tissue-engineered scaffolding made of cartilage cells, which have a limited ability to heal naturally, to replace defective cartilage tissue. Cartilage cells are extracted and seeded to the scaffold which is implanted into the body, where new cartilage tissue is grown along the structure. The study appears in the journal Artificial Organs.

The procedure was extremely successful in tested mice as the study found these scaffolds to be a far more effective means of regenerating cartilage than traditional therapy. The shrinkage of cartilage that occurs frequently in other tissue engineering methods, and often renders the replacement tissue wrongly-sized for implantation, did not occur in the study. The scaffolding allowed the newly grown cartilage to maintain its volume during cultivation and post-procedure.

"The cell-derived scaffold could provide a favorable environment for cartilage cells to maintain their characteristics while synthesizing cartilage in the scaffold structure in vivo," notes study author Dr. Byoung-Hyun Min. "Cell-derived scaffolding may hold great promise for the future. A variety of applications are possible for the engineering of cartilage tissue as the shape and porosity can be altered to suit the type of tissue required."

Source: Blackwell Publishing Ltd.

Explore further: Gamers helping in Ebola research

add to favorites email to friend print save as pdf

Related Stories

Finding the sweet spot for cartilage formation

Aug 13, 2014

Joint injuries often fail to mend properly when not given assistance. In particular, cartilage exhibits a poor capacity for self-repair. It is possible to stimulate regeneration by implanting synthetic scaffolds ...

Materials scientists turn to collagen

Jun 05, 2014

(Phys.org) —Miniature scaffolds made from collagen – the 'glue' that holds our bodies together – are being used to heal damaged joints, and could be used to develop new cancer therapies or help repair ...

New method to grow synthetic collagen unveiled

Sep 08, 2011

In a significant advance for cosmetic and reconstructive medicine, scientists at Rice University have unveiled a new method for making synthetic collagen. The new material, which forms from a liquid in as ...

Recommended for you

Gamers helping in Ebola research

12 hours ago

Months before the recent Ebola outbreak erupted in Western Africa, killing more than a thousand people, scientists at the University of Washington's Institute for Protein Design were looking for a way to stop the deadly virus.

Carcinogenic role of a protein in liver decoded

15 hours ago

The human protein EGFR controls cell growth. It has mutated in case of many cancer cells or exists in excessive numbers. For this reason it serves as a point of attack for target-oriented therapies. A study ...

A new way to diagnose malaria, using magnetic fields

Aug 31, 2014

Over the past several decades, malaria diagnosis has changed very little. After taking a blood sample from a patient, a technician smears the blood across a glass slide, stains it with a special dye, and ...

User comments : 0