Scientists develop 'exercise pill'

May 01, 2007

A U.S. scientist has created an "exercise pill" that activates a gene that tells cells to burn fat, making mice resistant to high-fat diet weight gains.

Salk Institute scientist Ronald Evans and colleagues said by giving ordinary adult mice a synthetic designed to mimic fat, he has been able to chemically switch on PPAR-d, the master regulator gene that controls the ability of cells to burn fat. Even when the mice are not active, turning on the chemical switch activates the same fat-burning process that occurs during exercise.

The resulting shift in energy balance makes the mice resistant to weight gain even on a high fat diet.

Evans, who presented the study Monday in Washington during the Experimental Biology 2007 meeting, said his findings might lead to a new approach to the treatment and prevention of human metabolic syndrome.

Copyright 2007 by United Press International

Explore further: Seniors successfully withdraw from meds

add to favorites email to friend print save as pdf

Related Stories

Pets and anesthesia

Mar 21, 2014

Have you been avoiding getting your pet regular dental care? You're not alone. Most pet owners understand that in animals—just as in people—good oral health is conducive to overall well-being, says Gillian Fraser, V00, ...

Conversion from bad fat to good fat

Apr 28, 2013

Scientists from ETH Zurich in Switzerland have shown for the first time that brown and white fat cells in a living organism can be converted from one cell type to the other. Their work, using mice as a model organism, provides ...

Recommended for you

Seniors successfully withdraw from meds

Sep 19, 2014

Elderly people have proved receptive to being de-prescribed medications, as part of a trial aimed at assessing the feasibility of withdrawal of medications among older people.

Flu vaccine for expectant moms a top priority

Sep 18, 2014

Only about half of all pregnant women in the U.S. get a flu shot each season, leaving thousands of moms-to-be and their babies at increased risk of serious illness.

Experts want restrictions on testosterone drug use (Update)

Sep 17, 2014

Federal health experts said Wednesday there is little evidence that testosterone-boosting drugs are effective for treating common signs of aging in men and that their use should be narrowed to exclude millions of Americans ...

User comments : 0