Avian flu vaccine developed for poultry

Dec 07, 2006

U.S. scientists say they've developed the first egg-injected vaccine to protect chickens against the avian influenza virus.

An Auburn University veterinary professor, Haroldo Toro, and researchers at Vaxin Inc. of Birmingham, Ala., say the vaccine would provide 100 percent protection once an outbreak's specific viral strain is identified.

"We have proven the principle, which is the major step in leading to commercially produced vaccine that could be vital to the poultry industry," Toro said. "When an outbreak occurs, we would determine the strain and quickly create a vaccine within three months specifically for it."

The researchers inserted a gene from a low pathogenic avian flu virus strain (H5N9) into a non-replicating human virus, a Vaxin proprietary technology, which was then injected into developing chicken embryos still in the egg.

When protection induced by the vaccine was tested against two highly pathogenic avian flu viruses -- a Vietnam H5N1 strain and a Mexican H5N2 strain -- the results showed 68 percent and 100 percent protection, in that order.

"Our results indicate that we can provide effective protection against any strain after incorporating the gene of the field strain into our vaccine construct," said Toro.

Copyright 2006 by United Press International

Explore further: Bristol-Myers earnings jump 27 percent, but stock falls

Related Stories

Radio silence as Russia tries to contact space cargo

23 minutes ago

Russia will try again in the coming hours to make contact with an unmanned cargo ship after communications were lost following the spacecraft's launch toward the International Space Station, NASA said Tuesday.

No-electric clothes washer appeals to pedal pushers

31 minutes ago

Did you say a washing machine "off the grid?" You mean a washing machine that does not need electricity? You work it with your foot? Small wonder that many sites this month have been picking up on the Yirego ...

ONR: Helping to train the future canine force

31 minutes ago

Canines have proven to be expert bomb detectors for U.S. troops in Iraq and Afghanistan. But with combat operations winding down, the Office of Naval Research's (ONR) Expeditionary Canine Sciences program ...

Recommended for you

Joint search for new antibiotics

8 hours ago

The WHO has identified antibiotic resistance as one of the three biggest threats to human health. Without new antibiotics, we risk returning to a situation in which every infection is life-threatening. The ...

Mylan rebuffs Teva again; calls bid low, insincere

Apr 27, 2015

Generic drug company Mylan rejected for the second time Monday a $40.1 billion takeover offer from Israeli pharmaceutical power Teva, just days after Mylan's own bid for rival Perrigo was rebuffed.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.