Discovery could lead to new leukaemia treatments

Nov 06, 2006

Deakin University scientists have identified a protein that could hold the key to new leukaemia treatments.

The protein--Stat5--was investigated at a laboratory at Deakin's Melbourne Campus at Burwood, as part of a multicentre international collaboration.

Leukaemia is a cancer caused by a proliferation of white blood cells. To understand and help prevent the disease, the Deakin researchers are looking for the responsible genes.

Head of the Deakin team, Associate Professor Alister Ward, said the discovery of how the protein acts provides a breakthrough in understanding the onset of leukaemia.

"We have found that Stat5 is responsible for making white blood cells overgrow in a particular disease setting that often precedes leukaemia," Associate Professor Ward explained.

"On top of this, we have also found that Stat5, when activated, is sufficient on its own to cause white blood cells to overgrow inside a whole organism.

"Together, these findings identify Stat5 as a major player in the process of leukaemia progression and is therefore a worthwhile target for intervention."

Associate Professor Ward said the next step in this research was to utilise the model systems established to develop new therapeutics.

Source: Research Australia

Explore further: Doubt cast over air pollution link between childhood leukemia and power lines

add to favorites email to friend print save as pdf

Related Stories

Will Apple Pay be mobile pay's kick-start?

5 hours ago

If anyone can get us to use our smartphones as wallets, it's Apple. That's what experts think about the recent launch of Apple Pay, the first mobile wallet to work on an iPhone.

Google execs discuss regulation, innovation and bobble-heads

7 hours ago

Eric Schmidt and Jonathan Rosenberg help run Google, one of the world's best-known, most successful - and most controversial - companies. They've just published a new book, "How Google Works," a guide to managing what they ...

Developing the battery of the future

8 hours ago

The search for the next generation of batteries has led researchers at the Canadian Light Source synchrotron to try new methods and materials that could lead to the development of safer, cheaper, more powerful, ...

Gamers' funding fuels meteoric rise of 'Star Citizen'

8 hours ago

Chris Roberts' brain spun out a grand vision: a rich, immersive galaxy; exquisite spaceships traversing between infinite star systems with thousands of computer gamers manning the cockpits, racing, dogfighting and defending ...

Recommended for you

Unlocking the secrets of pulmonary hypertension

9 hours ago

A UAlberta team has discovered that a protein that plays a critical role in metabolism, the process by which the cell generates energy from foods, is important for the development of pulmonary hypertension, a deadly disease.

New molecule sneaks medicines across the blood/brain barrier

14 hours ago

Delivering life-saving drugs across the blood-brain barrier (BBB) might become a little easier thanks to a new report published in the November 2014 issue of The FASEB Journal. In the report, scientists describe an antibo ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.