Discovery could lead to new leukaemia treatments

Nov 06, 2006

Deakin University scientists have identified a protein that could hold the key to new leukaemia treatments.

The protein--Stat5--was investigated at a laboratory at Deakin's Melbourne Campus at Burwood, as part of a multicentre international collaboration.

Leukaemia is a cancer caused by a proliferation of white blood cells. To understand and help prevent the disease, the Deakin researchers are looking for the responsible genes.

Head of the Deakin team, Associate Professor Alister Ward, said the discovery of how the protein acts provides a breakthrough in understanding the onset of leukaemia.

"We have found that Stat5 is responsible for making white blood cells overgrow in a particular disease setting that often precedes leukaemia," Associate Professor Ward explained.

"On top of this, we have also found that Stat5, when activated, is sufficient on its own to cause white blood cells to overgrow inside a whole organism.

"Together, these findings identify Stat5 as a major player in the process of leukaemia progression and is therefore a worthwhile target for intervention."

Associate Professor Ward said the next step in this research was to utilise the model systems established to develop new therapeutics.

Source: Research Australia

Explore further: Recombinant peptide for transplantation of pancreatic islets in mice models of diabetes

add to favorites email to friend print save as pdf

Related Stories

Italian olive tree disease stumps EU

2 hours ago

EU member states are divided on how to stop the spread of a disease affecting olive trees in Italy that could result in around a million being cut down, officials said Friday.

Festo has BionicANTs communicating by the rules for tasks

2 hours ago

Germany-based automation company Festo, focused on technologies for tasks, turns to nature for inspiration, trying to take the cues from how nature performs tasks so efficiently. "Whether it's energy efficiency, ...

Jury decides Silicon Valley firm did not discriminate

3 hours ago

A jury decided Friday that a prestigious venture capital firm did not discriminate or retaliate against a female employee in a case that shined a light on gender imbalance and working conditions for women ...

Intel in talks with Altera on tie-up

3 hours ago

US tech giant Intel is in talks with rival Altera on a tie-up to broaden the chipmaker's product line amid growth in Internet-connected devices, the Wall Street Journal reported Friday.

Recommended for you

Novel nanoparticle therapy promotes wound healing

Mar 26, 2015

An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal wounds compared to no treatment at all. Details of the therapy, ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.