Pfizer drug found with serious side effect

Nov 01, 2006

U.S. pharmaceutical company Pfizer Inc. says clinical trials of its heart medication torcetrapib suggest the drug has a potentially serious side effect.

Pfizer says the trials involving what is viewed as the company's most important pending drug confirm its increases blood pressure, The New York Times reported.

Analysts say Pfizer, the world's largest drug company. Expects torcetrapib to replace the $13 billion in annual sales from the cholesterol-lowering drug Lipitor, which loses patent protection in 2010.

Pfizer's stock dropped 2 percent after the Tuesday announcement by the company, which has been researching torcetrapib for a decade and is spending $800 million to develop it, the Times said.

Pfizer said it still expects to submit the medicine for federal approval sometime during the second half of next year, with an approval possible in 2008.

Pfizer hopes to show a combination of torcetrapib and Lipitor can reduce the formation of arterial plaque.

Copyright 2006 by United Press International

Explore further: HHS leaders call for expanded use of medications to combat opioid overdose epidemic

add to favorites email to friend print save as pdf

Related Stories

New drug produces steep drop in bad cholesterol

Nov 17, 2010

(AP) -- An experimental drug boosted good cholesterol so high and dropped bad cholesterol so low in a study that doctors were stunned and voiced renewed hopes for an entirely new way of preventing heart attacks ...

More 'good' cholesterol is not always good for your health

May 25, 2010

(PhysOrg.com) -- We've all heard about the importance of raising HDL, or the so-called "good" cholesterol, and lowering LDL, or "bad" cholesterol, to improve heart health. While we've come to assume HDL cholesterol ...

Recommended for you

FDA reconsiders behavior-modifying 'shock devices'

11 hours ago

(HealthDay)—They're likened to a dog's "shock collar" by some and called a "life-saving treatment" by others. But the days of electro-shock devices as a tool for managing hard-to-control behavior in people ...

FDA proposes accelerated medical device approval plan

Apr 23, 2014

(HealthDay)—The U.S. Food and Drug Administration has proposed a new program that would provide expedited access to high-risk medical devices intended for patients with serious conditions whose medical ...

Targeting drugs to reduce side effects

Apr 23, 2014

(Medical Xpress)—Consider ice cream – the base of which is frozen cream. Ingredients are then added to make different flavours. All these flavours are distinctly different but are created from the same foundation.

User comments : 0

More news stories

Google+ boss leaving the company

The executive credited with bringing the Google+ social network to life is leaving the Internet colossus after playing a key role there for nearly eight years.