Anti-cancer virus kills brain cancer cells

Nov 01, 2006

Canadian researchers have found a cancer-fighting virus called VSV kills the most malignant form of brain cancer in mice.

The University of Calgary researchers, led by medical oncologist Dr. Peter Forsyth, also discovered the virus can be given intravenously to target invasive tumor cells.

The research team first modified the virus by altering one of the genes to make it safer in normal cells, but still able to kill cancer cells. Using the intravenous method of delivery, they were able to target the main tumor, as well as the tumor cells that had spread from the main mass.

The researchers tested VSV on 14 cell lines of malignant glioma and found the virus infected and killed all cell lines. The normal cell lines -- those not containing malignant glioma cells -- were not affected.

The study is published in the November issue of the Journal of the National Cancer Institute.

Copyright 2006 by United Press International

Explore further: Survival differences seen for advanced-stage laryngeal cancer

add to favorites email to friend print save as pdf

Related Stories

Senators get no clear answers on air bag safety

3 hours ago

There were apologies and long-winded explanations, but after nearly four hours of testimony about exploding Takata air bags, senators never got a clear answer to the question most people have: whether or ...

Nicaragua: Studies say canal impact to be minimal

4 hours ago

Officials said Thursday that studies have determined a $40 billion inter-oceanic canal across Nicaragua will have minimal impact on the environment and society, and construction is to begin next month.

Former Brown dean whose group won Nobel Prize dies

4 hours ago

David Greer, a doctor who co-founded a group that won the 1985 Nobel Peace Prize for working to prevent nuclear war and who helped transform the medical school at Brown University, has died. He was 89.

Recommended for you

Survival differences seen for advanced-stage laryngeal cancer

13 minutes ago

The five-year survival rate for advanced-stage laryngeal cancer was higher than national levels in a small study at a single academic center performing a high rate of surgical therapy, including a total laryngectomy (removal ...

Gene test aids cancer profile

9 hours ago

The first round of chemotherapy did little to suppress Ron Bose's leukemia. The second round, with 10 times the dose, knocked the proliferating blast cells down, but only by half.

Hospital volume not linked to costs of cancer surgery

Nov 26, 2014

(HealthDay)—Hospital surgical volume does not appear to correlate with Medicare payments for cancer surgery, according to research published online Nov. 24 in the Journal of Clinical Oncology.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.