Drug class not effective for Alzheimer's

Oct 12, 2006

A study funded by the National Institute of Mental Health in Bethesda, Md., says antipsychotic drugs used to treat Alzheimer's patients are mostly ineffective.

The study, published in the New England Journal of Medicine, concluded that the drugs benefit very few patients with the degenerative illness, and the helpful effects are canceled out by frequent side effects, The Washington Post reported Thursday.

The researchers studied 421 Alzheimer's patients who suffered from disabling agitation, delusions or hallucinations. The patients were randomly assigned a placebo or one of three antipsychotic drugs -- Zyprexa from Eli Lilly; Seroquel from AstraZeneca; and Risperdal from Janssen Pharmaceutical, The New York Times reported.

Lead study author Lon Schneider, a professor of psychiatry, neurology and gerontology at the University of Southern California School of Medicine, said "there were no significant differences between the groups with regard to improvement" after 12 weeks of treatment, the Times said.

Spokesmen for the three pharmaceutical manufacturers said the drugs were not approved by the Food and Drug Administration for Alzheimer's use and the companies did not recommend them for that function.

Copyright 2006 by United Press International

Explore further: Drug prices to treat multiple sclerosis soar, point to larger problem

Related Stories

Genetic road map may bring about better cotton crops

13 minutes ago

A University of Texas at Austin scientist, working with an international research team, has developed the most precise sequence map yet of U.S. cotton and will soon create an even more detailed map for navigating ...

Recommended for you

Rising antibiotic shortages raise concerns about patient care

Apr 23, 2015

Shortages of key antibiotics, including gold-standard therapies and drugs used to treat highly resistant infections, are on the rise, according to a new study of shortages from 2001 to 2013 published in Clinical Infectious Di ...

Study supports HPV vaccination guidelines

Apr 21, 2015

(HealthDay)—New research finds that young women who get the HPV vaccine gain significant protection against infection in three parts of the body if they haven't already been exposed to the human papillomavirus.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.