New study hopeful on neural stem cells

Aug 05, 2006

Neural stem cells derived from federally approved human embryonic cells are inferior to stem cells derived from donated fetal tissue, a new study found.

Researchers from the Institute for Stem Cell Biology and Medicine at UCLA conditioned cells from the federally approved line to differentiate into neural stem cells, a process that may someday be used to treat diseases such as Parkinson's and Alzheimer's.

However, the neural stem cells showed a lower level of a metabolic gene called CPT 1A, which can cause hypoglycemia in humans, researchers said.

The new study may bring scientists closer to growing neural and other stem cells in the lab so they replicate normal cells which function normally, said Guoping Fan, an assistant professor of human genetics and a researcher in UCLA's stem cell institute.

"This study is a very important first step in looking at the differentiation process in neural stem cells," said Fan, senior author of the study. "Now we have a direct measurement of the types of cells that eventually, we hope, will be used for transplantation."

The study appears this week in an early online edition of the journal Human Molecular Genetics.

Copyright 2006 by United Press International

Explore further: NY and NJ say they will require Ebola quarantines

add to favorites email to friend print save as pdf

Related Stories

Special chromosomal structures control key genes

Oct 09, 2014

Within almost every human cell is a nucleus six microns in diameter—about one 300th of a human hair's width—that is filled with roughly three meters of DNA. As the instructions for all cell processes, the DNA must be ...

Sugar mimics guide stem cells toward neural fate

Jul 30, 2014

Embryonic stem cells can develop into a multitude of cells types. Researchers would like to understand how to channel that development into the specific types of mature cells that make up the organs and other structures of ...

Stem cells use 'first aid kits' to repair damage

Sep 18, 2014

Stem cells hold great promise as a means of repairing cells in conditions such as multiple sclerosis, stroke or injuries of the spinal cord because they have the ability to develop into almost any cell type. ...

Recommended for you

Two US states order tough Ebola quarantine rules

4 hours ago

New York and New Jersey on Friday ordered a mandatory quarantine for medics who treated victims of Ebola in West Africa, after the deadly virus spread to America's largest city.

NY and NJ say they will require Ebola quarantines

22 hours ago

The governors of New Jersey and New York on Friday ordered a mandatory, 21-day quarantine for all doctors and other arriving travelers who have had contact with Ebola victims in West Africa.

User comments : 0