Researchers find Down, Alzheimer's link

Jul 06, 2006

Stanford University researchers say they may have found a key that causes people with Down syndrome to develop early Alzheimer's disease.

The findings, published in Thursday's edition of the journal Neuron, are said to offer a lengthened target for drug research and hope for treatment because people with Down syndrome are living longer than before.

Scientists say Down syndrome affects about 350,000 Americans, causing mental retardation and a risk of premature Alzheimer's dementia, The Wall Street Journal reports.

Stanford's Ahmad Salehi, Jean-Dominique Delacroix and William C. Mobley, lead authors of the study, zeroed in on a gene known as App (for amyloid precursor protein), already a known culprit in other forms of Alzheimer's.

Copyright 2006 by United Press International

Explore further: How drinking behavior changes through the years

add to favorites email to friend print save as pdf

Related Stories

Unlocking the secret(ase) of building neural circuits

Jan 18, 2011

Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease -- early-onset familial Alzheimer's -- which can strike people as early as their 30s. In their latest study, researchers ...

Recommended for you

Teenage TV audiences and energy drink advertisements

22 minutes ago

Researchers at Dartmouth College examined a database of television advertisements broadcast between March 2012 and February 2013 on 139 network and cable channels and found that more than 608 hours of advertisements for energy ...

How drinking behavior changes through the years

8 hours ago

In the UK, frequent drinking becomes more common in middle to old age, especially amongst men, according to research published in the open access journal, BMC Medicine. Doctors are seeing a growing number ...

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.