Skin stem cells found transplantable

Jun 14, 2006

Canadian scientists say they've determined stem cells from adult skin can be transplanted and remain functional.

The researchers say such stem cells create neural cell types that function in mouse models of disease.

Scientists at Toronto's Hospital for Sick Children, the University of Calgary, and the University of Toronto previously discovered what type of cells can be made from skin-derived precursors, or SKPs. In addition to generating the peripheral nervous system, neural crest stem cells generate other tissues, such as bone, cartilage, and even part of the heart.

The research team found SKPs can efficiently generate a type of glial cell -- called Schwann cells -- that can myelinate demyelinated axons and have been shown to provide a good growth environment for injured central nervous system axons that do not regenerate.

"Our finding ... raises the possibility that we could treat humans with Schwann cells derived from human skin stem cells, and perhaps even use the patient's own skin to generate Schwann cells for treatment," said Dr. Freda Miller, the study's principal investigator.

The research is reported in The Journal of Neuroscience.

Copyright 2006 by United Press International

Explore further: Senegal monitors contacts of 1st Ebola patient

add to favorites email to friend print save as pdf

Related Stories

How the zebrafish gets its stripes

Aug 28, 2014

The zebrafish, a small fresh water fish, owes its name to a striking pattern of blue stripes alternating with golden stripes. Three major pigment cell types, black cells, reflective silvery cells, and yellow ...

Tissue regeneration using anti-inflammatory nanomolecules

Aug 22, 2014

Anyone who has suffered an injury can probably remember the after-effects, including pain, swelling or redness. These are signs that the body is fighting back against the injury. When tissue in the body is damaged, biological ...

Venom gets good buzz as potential cancer-fighter

Aug 11, 2014

Bee, snake or scorpion venom could form the basis of a new generation of cancer-fighting drugs, scientists will report here today. They have devised a method for targeting venom proteins specifically to malignant cells while ...

On the frontiers of cyborg science

Aug 10, 2014

No longer just fantastical fodder for sci-fi buffs, cyborg technology is bringing us tangible progress toward real-life electronic skin, prosthetics and ultraflexible circuits. Now taking this human-machine concept to an ...

Recommended for you

Mechanical heart valves increase pregnancy risk

1 hour ago

The fact that mechanical heart valves increase risks during and after pregnancy, has been confirmed by data from the ROPAC registry presented for the first time today in an ESC Congress Hot Line session by Professor Jolien ...

Senegal monitors contacts of 1st Ebola patient

11 hours ago

Senegalese authorities on Monday were monitoring everyone who was in contact with a student infected with Ebola who crossed into the country, and who has lost three family members to the disease.

User comments : 0