UB gets federal grant for stem cell study

Jun 13, 2006

A stem cell biologist at the University at Buffalo has received a $1.98 million federal research grant.

Te-Chung Lee, associate professor of biochemistry, will investigate the potential of bone marrow-derived adult stem cells to treat the serious heart malfunction known as hibernating myocardium.

Hibernating myocardium is a condition in which heart cells that have experienced reduced blood flow over an extended period of time due to narrowed coronary arteries adapt by down-regulating metabolism while remaining functionally viable.

Previous work at the university has shown restoring normal blood flow to such "hibernating" regions improves function. However, scientists also found cells in the left ventricle, the heart's main pumping chamber, often do not return to normal, leaving the heart compromised.

Lee and colleagues will investigate whether transplanting a swine model's own bone marrow stem cells into the down-regulated tissue can change the myocardial adaptive responses and improve the function of the hibernating myocardium.

The grant is being provided by the National Institutes of Health.

Copyright 2006 by United Press International

Explore further: US teen birth rate drops to record low

add to favorites email to friend print save as pdf

Related Stories

Nanostructures with living cells

Feb 05, 2013

Using laser technology, Aleksandr Ovsianikov from the Vienna University of Technology wants to create microstructures with embedded living cells.

Racing to identify species as biodiversity shrinks

Jan 07, 2013

A little more than 39 years ago, on December 28, 1973, the Endangered Species Act was enacted to conserve threatened and endangered species and their ecosystems. To honor this anniversary, Daphne Fautin of ...

Report: California stem cell agency needs overhaul

Dec 07, 2012

(AP)—California has transformed into a major player in stem cell research, but the taxpayer-funded institute responsible has "significant deficiencies" in how research dollars are distributed, experts said Thursday.

Recommended for you

US teen birth rate drops to record low

15 minutes ago

US teen births have dropped to a record low, but the country still has one of the highest rates among developed nations, the US Centers for Disease Control and Prevention said Thursday.

Systematic screening of med adherence will ID barriers

13 hours ago

(HealthDay)—Implementation of systematic monitoring for medication adherence will allow for identification of barriers to adherence and tailoring of interventions, according to a viewpoint piece published ...

User comments : 0

More news stories

Brain can be trained in compassion, study shows

Until now, little was scientifically known about the human potential to cultivate compassion—the emotional state of caring for people who are suffering in a way that motivates altruistic behavior.

Submerged structure stumps Israeli archaeologists

The massive circular structure appears to be an archaeologists dream: a recently discovered antiquity that could reveal secrets of ancient life in the Middle East and is just waiting to be excavated.

Solar plane sets distance record on US tour

The first manned aircraft that can fly day and night powered only by solar energy set a new distance record Thursday when it landed after the second leg of a cross-country US tour.